Grande G A, Ling L J
Hennepin Regional Poison Center, Minneapolis, Minnesota.
J Toxicol Clin Toxicol. 1987;25(6):473-81. doi: 10.3109/15563658708992650.
Large volumes of fluid have been recommended to aid rapid ipecac-induced emesis, however, large volume intake may also have deleterious effects. We prospectively studied 121 children treated at home by a regional poison center to determine if a relationship existed between fluid volume and time to emesis. These children were treated in the usual manner except that parents were asked to measure the volume of fluid given and to note the time that fluid was given and the time of first emesis. The time ranged from 6 to 58 minutes (mean 20.6) with two who failed to respond and the volume ranged from 0 to 28 ounces (mean 6.7 ounces). In children who respond to ipecac, there is no significant relationship between the amount of fluid given and the time until emesis. We conclude that the traditional recommendation of forcing fluid with syrup of ipecac does not hasten emesis in children.
大量液体被推荐用于帮助快速诱导吐根糖浆催吐,然而,大量摄入液体也可能有有害影响。我们前瞻性地研究了一家地区中毒控制中心在家中治疗的121名儿童,以确定液体量与催吐时间之间是否存在关联。这些儿童以常规方式接受治疗,只是要求家长测量给予的液体量,并记录给予液体的时间和首次呕吐的时间。时间范围为6至58分钟(平均20.6分钟),有两名儿童无反应,液体量范围为0至28盎司(平均6.7盎司)。在对吐根糖浆有反应的儿童中,给予的液体量与呕吐前的时间之间没有显著关联。我们得出结论,传统的用吐根糖浆强迫摄入液体的建议并不能加速儿童的呕吐。