Department of Physics and Astronomy, University of Georgia, Athens, GA 30602, USA.
Nanoscale. 2017 Oct 5;9(38):14710-14721. doi: 10.1039/c7nr06067j.
Using the difference of the polarization transmission spectra of elliptical nanohole arrays (ENAs), the figure of merit (FOM) of the sensor performance of ENA can be significantly improved, and is inversely proportional to the measurement resolution. By optimizing the aspect ratio of the elliptical holes, Ag thickness, substrate-effect, and adhesive layer, the sensitivity, FOM, and relative sensitivity of the ENA can be improved to be 775 nm RIU, 705 RIU, and 70.23%, respectively, with an excellent linear dependence on the change of refractive index. Such a high-performance sensor also can be used in monitoring the molecule adsorption and RNA hybridization, revealing a highly localized near-field enhancement. This will benefit the sensing of surface-specific binding events in biologic detection and medical diagnosis.
利用椭圆纳米孔阵列（ENAs）的偏振透射光谱的差异，可以显著提高传感器性能的品质因数（FOM），并且与测量分辨率成反比。通过优化椭圆孔的纵横比、Ag 厚度、基底效应和胶黏层，可以提高 ENA 的灵敏度、FOM 和相对灵敏度，分别为 775nm RIU、705RIU 和 70.23%，并且对折射率的变化具有出色的线性依赖性。这种高性能传感器还可以用于监测分子吸附和 RNA 杂交，揭示高度局域的近场增强。这将有助于生物检测和医学诊断中表面特定结合事件的传感。
