叶酸-Au@聚（丙烯酸）/介孔磷酸钙 Janus 纳米粒子的可调谐制备用于癌细胞的 CT 成像和主动靶向化疗。
Tunable fabrication of folic acid-Au@poly(acrylic acid)/mesoporous calcium phosphate Janus nanoparticles for CT imaging and active-targeted chemotherapy of cancer cells.
机构信息
National & Local United Engineering Laboratory for Power Battery, Department of Chemistry, Northeast Normal University, Changchun, 130024, P. R. China.
出版信息
Nanoscale. 2017 Oct 5;9(38):14322-14326. doi: 10.1039/c7nr05382g.
PMID:28948263
Abstract
A novel, facile and reproducible method was explored to construct uniform folic acid-Au@poly(acrylic acid)/mesoporous calcium phosphate Janus nanoparticles (FA-Au@PAA/mCaP JNPs), which act as an efficient nanoplatform for X-ray computed tomography (CT) imaging and active-targeted chemotherapy in vitro.
摘要
探索了一种新颖、简便且可重现的方法来构建均匀的叶酸-Au@聚丙烯酸/介孔磷酸钙双节纳米粒子（FA-Au@PAA/mCaP JNPs），其可用作体外 X 射线计算机断层扫描（CT）成像和主动靶向化疗的有效纳米平台。
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