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[2013 - 2016年捷克共和国人群中单核细胞增生李斯特菌的分子流行病学特征及多样性]

[Molecular-epidemiological characteristics and diversity of Listeria monocytogenes in the human population in the Czech Republic in 2013-2016].

作者信息

Gelbíčová T, Tomáštíková Z, Karpíšková R

出版信息

Epidemiol Mikrobiol Imunol. 2017 Fall;66(3):146-148.

Abstract

Listeria monocytogenes is the cause of a serious foodborne infection with a high fatality rate. The aim of this study was to assess the diversity of human isolates of L. monocytogenes recovered in the Czech Republic from 2013 to 2016 by molecular biological methods. Most cases of listeriosis were caused by strains of serotype 1/2a (58 %) from clonal complex CC8 (28 %) and serotype 4b (28 %) from CC6 (16 %). The results of macrorestriction analysis confirmed primarily the occurrence of sporadic cases of listeriosis. A local outbreak of listeriosis was reported in the Moravian-Silesian Region. Real-time molecular subtyping methods have proved helpful in the investigation of Listeria outbreaks.

摘要

单核细胞增生李斯特菌是一种严重食源性感染的病原菌,致死率很高。本研究旨在通过分子生物学方法评估2013年至2016年在捷克共和国分离出的人源单核细胞增生李斯特菌的多样性。大多数李斯特菌病病例由克隆复合体CC8(28%)中的血清型1/2a菌株(58%)和CC6(16%)中的血清型4b菌株(28%)引起。宏观限制性分析结果主要证实了李斯特菌病散发病例的发生。摩拉维亚-西里西亚地区报告了一起李斯特菌病局部暴发。实时分子分型方法已被证明有助于调查李斯特菌暴发。

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