2012-2016 年捷克共和国与火鸡肉产品有关的李斯特菌病暴发。
An outbreak of listeriosis linked to turkey meat products in the Czech Republic, 2012-2016.
机构信息
Department of Bacteriology,Veterinary Research Institute,Hudcova 70,621 00 Brno,Czech Republic.
European Centre for Disease Prevention and Control (ECDC),Gustav III:s Boulevard 40,16973 Solna,Sweden.
出版信息
Epidemiol Infect. 2018 Aug;146(11):1407-1412. doi: 10.1017/S0950268818001565. Epub 2018 Jun 18.
Abstract
Since 2012-2016 an increased number of listeriosis cases, especially from one region of the Czech Republic, were observed. Most of them were caused by strains of serotype 1/2a, clonal complex 8, indistinguishable by pulsed-field gel electrophoresis. Twenty-six human cases were reported, including two neonatal cases in twins. Three cases were fatal. The typing of Listeria monocytogenes isolates from food enabled to confirm a turkey meat delicatessen as the vehicle of infection for this local outbreak in the Moravian-Silesian Region. The food strains belonging to identical pulsotype were isolated from ready-to-eat turkey meat products packaged by the same producer between 2012 and 2016. This fact confirms that the described L. monocytogenes outbreak strain probably persisted in the environment of the aforementioned food-processing plant over several years. Whole-genome sequencing confirmed a very close relationship (zero to seven different alleles) between isolates from humans, foods and swabs from the environment of the food-processing plant under investigation.
摘要
自 2012 年至 2016 年，观察到食源性李斯特菌病病例数量增加，尤其是在捷克共和国的一个地区。其中大多数由血清型 1/2a、克隆复合体 8 的菌株引起，脉冲场凝胶电泳无法区分。报告了 26 例人类病例，包括双胞胎中的 2 例新生儿病例。3 例死亡。从食品中分离出的单核细胞增生李斯特菌的分型可证实火鸡肉熟食是该地区在摩拉维亚-西里西亚地区局部暴发的感染源。在 2012 年至 2016 年间，由同一生产商包装的即食火鸡肉产品中分离出了属于相同脉冲型的食品菌株。这一事实证实，所描述的单核细胞增生李斯特菌暴发菌株可能在上述食品加工厂的环境中持续存在了数年。全基因组测序证实，来自人类、食品以及食品加工厂环境拭子的分离株之间存在非常密切的关系（零到七个不同等位基因）。
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The European Union summary report on trends and sources of zoonoses, zoonotic agents and food-borne outbreaks in 2016.欧盟2016年人畜共患病、人畜共患病原体及食源性疾病暴发的趋势与来源总结报告
EFSA J. 2017 Dec 12;15(12):e05077. doi: 10.2903/j.efsa.2017.5077. eCollection 2017 Dec.
2
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3
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Nat Microbiol. 2016 Oct 10;2:16185. doi: 10.1038/nmicrobiol.2016.185.
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6
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7
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PLoS One. 2016 Mar 8;11(3):e0151117. doi: 10.1371/journal.pone.0151117. eCollection 2016.
9
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