• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

作为自闭症科学研究环境的母体

The maternal body as environment in autism science.

作者信息

Lappé Martine

机构信息

Center for Research on Ethical, Legal and Social Implications of Psychiatric, Neurologic and Behavioral Genetics, Columbia University, New York, NY, USA.

出版信息

Soc Stud Sci. 2016 Oct;46(5):675-700. doi: 10.1177/0306312716659372. Epub 2016 Aug 20.

DOI:10.1177/0306312716659372
PMID:28948883
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5618715/
Abstract

Research on autism and environmental risk factors has expanded substantially in recent years. My analysis draws attention to the regimes of perceptibility that shape how the environment is materialized in post-genomic science. I focus on how more complex narratives of autism's causes and social anxieties surrounding child development have helped situate autism risk in women's bodies before and during pregnancy. This has resulted in what I call the maternal body as environment in autism science. I show that this figure involves three characteristics: the molecularization of the environment, an individualization of risk, and the internalization of responsibility. I argue that these three features point to a new spatial and temporal politics of risk and responsibility that may heighten social and medical surveillance of women's bodies and decisions, eclipsing larger questions about the uneven distribution of exposures in society and more holistic understandings of health that include neurodiversity. I conclude by considering what the maternal body as environment signals for women, social justice, and the politics of environmental health in the post-genomic era.

摘要

近年来,关于自闭症与环境风险因素的研究有了大幅扩展。我的分析关注的是那些塑造环境在后基因组科学中如何物质化的可感知性机制。我着重探讨自闭症成因的更复杂叙述以及围绕儿童发育的社会焦虑如何在孕期前后将自闭症风险定位在女性身体上。这就产生了我所谓的自闭症科学中作为环境的母体身体。我指出这个概念包含三个特征:环境的分子化、风险的个体化以及责任的内化。我认为这三个特征指向了一种新的风险与责任的时空政治,这种政治可能会加强对女性身体及决策的社会和医学监督,从而使关于社会中暴露分布不均的更大问题以及包括神经多样性在内的更全面的健康理解黯然失色。最后,我思考了作为环境的母体身体对后基因组时代的女性、社会正义以及环境健康政治意味着什么。

相似文献

1
The maternal body as environment in autism science.作为自闭症科学研究环境的母体
Soc Stud Sci. 2016 Oct;46(5):675-700. doi: 10.1177/0306312716659372. Epub 2016 Aug 20.
2
Autism risk factors: genes, environment, and gene-environment interactions.自闭症风险因素:基因、环境以及基因-环境相互作用。
Dialogues Clin Neurosci. 2012 Sep;14(3):281-92. doi: 10.31887/DCNS.2012.14.3/pchaste.
3
Maternal Chemical and Drug Intolerances: Potential Risk Factors for Autism and Attention Deficit Hyperactivity Disorder (ADHD).母体化学物质和药物不耐受:自闭症和注意力缺陷多动障碍(ADHD)的潜在风险因素。
J Am Board Fam Med. 2015 Jul-Aug;28(4):461-70. doi: 10.3122/jabfm.2015.04.140192.
4
Characterizing maternal isolation-induced ultrasonic vocalizations in a gene-environment interaction rat model for autism. characterizing 母体隔离诱导的超声发声在自闭症的基因-环境相互作用大鼠模型中。
Genes Brain Behav. 2023 Jun;22(3):e12841. doi: 10.1111/gbb.12841. Epub 2023 Feb 7.
5
Associations among maternal pre-pregnancy body mass index, gestational weight gain and risk of autism in the Han Chinese population.母亲孕前体重指数、孕期体重增加与汉族人群孤独症风险的关系。
BMC Psychiatry. 2018 Jan 17;18(1):11. doi: 10.1186/s12888-018-1593-2.
6
"We were on our own": Mothers' experiences navigating the fragmented system of professional care for autism.“我们只能靠自己”:母亲为自闭症寻求专业护理时面临的零碎系统。
Soc Sci Med. 2018 Oct;215:61-68. doi: 10.1016/j.socscimed.2018.08.039. Epub 2018 Sep 1.
7
Association of maternal exposure to childhood abuse with elevated risk for autism in offspring.母亲在儿童时期遭受虐待与后代自闭症风险升高有关。
JAMA Psychiatry. 2013 May;70(5):508-15. doi: 10.1001/jamapsychiatry.2013.447.
8
Autism and the environment: challenges and opportunities for research.自闭症与环境:研究的挑战与机遇
Pediatrics. 2008 Jun;121(6):1225-9. doi: 10.1542/peds.2007-3000.
9
Etiological implication of maternal age and birth order in infantile autism.母亲年龄和出生顺序对婴幼儿自闭症的病因学影响
J Autism Dev Disord. 1983 Mar;13(1):57-65. doi: 10.1007/BF01531359.
10
Annual Research Review: Shifting from 'normal science' to neurodiversity in autism science.年度研究综述:自闭症科学研究从“常规科学”转向神经多样性。
J Child Psychol Psychiatry. 2022 Apr;63(4):381-396. doi: 10.1111/jcpp.13534. Epub 2021 Nov 3.

引用本文的文献

1
'Our biology is listening': biomarkers as molecular vestiges of early life and the production of positive childhood experiences in behavioral epigenetics.“我们的生物学在倾听”:作为早期生命分子遗迹的生物标志物与行为表观遗传学中积极童年经历的产生。
Biosocieties. 2025;20(2):223-247. doi: 10.1057/s41292-024-00337-y. Epub 2024 Aug 31.
2
Categorical misalignment: Making autism(s) in big data biobanking.分类失调:在大数据生物样本库中构建自闭症谱系障碍
Soc Stud Sci. 2025 Apr;55(2):209-237. doi: 10.1177/03063127241288223. Epub 2024 Oct 7.
3
The Temporal Politics of Placenta Epigenetics: Bodies, Environments and Time.

本文引用的文献

1
Looping Genomes: Diagnostic Change and the Genetic Makeup of the Autism Population.循环基因组:自闭症群体的诊断变化与基因构成
AJS. 2016 Mar;121(5):1416-71. doi: 10.1086/684201.
2
How The Genome Got a Life Span.基因组是如何拥有寿命的。
New Genet Soc. 2015 Apr 3;34(2):152-176. doi: 10.1080/14636778.2015.1034851.
3
Paternal age and mental health of offspring.父亲年龄与子代心理健康。
胎盘表观遗传学的时间政治学:身体、环境与时间
Body Soc. 2023 Jun;29(2):49-76. doi: 10.1177/1357034x211068883. Epub 2022 Jun 13.
4
Acid-Responsive Dual-Targeted Nanoparticles Encapsulated Aspirin Rescue the Immune Activation and Phenotype in Autism Spectrum Disorder.载阿司匹林的酸响应型双重靶向纳米颗粒拯救自闭症谱系障碍中的免疫激活和表型。
Adv Sci (Weinh). 2022 May;9(14):e2104286. doi: 10.1002/advs.202104286. Epub 2022 Mar 13.
5
Environmental Politics of Reproduction.生殖的环境政治学
Annu Rev Anthropol. 2019 Oct;48:133-150. doi: 10.1146/annurev-anthro-102218-011346. Epub 2019 Jul 12.
6
Polygenic risk-stratified screening for cancer: Responsibilization in public health genomics.多基因风险分层筛查癌症:公共卫生基因组学中的责任。
Soc Stud Sci. 2019 Aug;49(4):605-626. doi: 10.1177/0306312719858404. Epub 2019 Jun 24.
7
The paradox of care in behavioral epigenetics: Constructing early-life adversity in the lab.行为表观遗传学中的关怀悖论:在实验室中构建早期生活逆境。
Biosocieties. 2018 Dec;13(4):698-714. doi: 10.1057/s41292-017-0090-z. Epub 2018 May 9.
Fertil Steril. 2015 Jun;103(6):1392-6. doi: 10.1016/j.fertnstert.2015.04.015. Epub 2015 May 5.
4
Lifestyle, pregnancy and epigenetic effects.生活方式、妊娠与表观遗传效应。
Epigenomics. 2015;7(1):85-102. doi: 10.2217/epi.14.71.
5
Whole-genome sequencing of quartet families with autism spectrum disorder.孤独症谱系障碍四重家庭的全基因组测序。
Nat Med. 2015 Feb;21(2):185-91. doi: 10.1038/nm.3792. Epub 2015 Jan 26.
6
Infancy, autism, and the emergence of a socially disordered body.婴儿期、自闭症与社会失调身体的出现
Soc Sci Med. 2015 Oct;143:279-86. doi: 10.1016/j.socscimed.2014.07.050. Epub 2014 Jul 22.
7
Prevalence of autism spectrum disorder among children aged 8 years - autism and developmental disabilities monitoring network, 11 sites, United States, 2010.8 岁儿童自闭症谱系障碍患病率 - 自闭症和发育障碍监测网络,11 个地点,美国,2010 年。
MMWR Surveill Summ. 2014 Mar 28;63(2):1-21.
8
Neurobehavioural effects of developmental toxicity.发育毒性的神经行为效应。
Lancet Neurol. 2014 Mar;13(3):330-8. doi: 10.1016/S1474-4422(13)70278-3. Epub 2014 Feb 17.
9
Measuring personal chemical exposures through biomonitoring: the experiences of research participants.通过生物监测测量个人化学物质暴露情况:研究参与者的经历。
Qual Health Res. 2014 Mar;24(3):329-44. doi: 10.1177/1049732314521899. Epub 2014 Feb 18.
10
MORE AND LESS THAN EQUAL: How Men Factor in the Reproductive Equation.大于与小于平等:男性在生殖等式中的因素
Gend Soc. 2013 Nov 12;27(6). doi: 10.1177/0891243213484510.