Department of Electrical and Computer Engineering, University of California, San Diego, La Jolla, California 92093, USA.
Nanoscale. 2017 Oct 12;9(39):14907-14912. doi: 10.1039/c7nr03654j.
Localized plasmonic structured illumination microscopy (LPSIM) is a recently developed super resolution technique that demonstrates immense potential via arrays of localized plasmonic antennas. Microlens microscopy represents another distinct approach for improving resolution by introducing a spherical lens with a large refractive index to boost the effective numerical aperture of the imaging system. In this paper, we bridge together the LPSIM and optically trapped spherical microlenses, for the first time, to demonstrate a new super resolution technique for surface imaging. By trapping and moving polystyrene and TiO microspheres with optical tweezers on top of a LPSIM substrate, the new imaging system has achieved a higher NA and improved resolution.
局域表面等离子体结构光照明显微镜（LPSIM）是一种最近发展起来的超分辨率技术，通过局域等离子体天线阵列显示出巨大的潜力。微透镜显微镜是另一种通过引入具有大折射率的球形透镜来提高成像系统有效数值孔径以提高分辨率的独特方法。在本文中，我们首次将 LPSIM 和光捕获球形微透镜结合在一起，展示了一种用于表面成像的新超分辨率技术。通过在 LPSIM 衬底上用光镊捕获和移动聚苯乙烯和 TiO 微球，新的成像系统实现了更高的 NA 和更高的分辨率。
