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从临床流行病学到实践建议：肛门癌前病变管理中的知识差距与不确定性

From clinical epidemiology to practice recommendations: Knowledge gaps and uncertainty in the management of anal precancers.

作者信息

Wentzensen Nicolas, Clarke Megan A

机构信息

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland.

出版信息

Cancer. 2017 Dec 1;123(23):4530-4534. doi: 10.1002/cncr.31033. Epub 2017 Sep 26.

DOI:10.1002/cncr.31033
PMID:28949415
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8771459/
Abstract

We discuss the existing data on anal precancers and demonstrate the impact of evidence gaps and uncertainty on a clinical decision model developed to provide clinical guidance for management of anal precancers.

摘要

我们讨论了关于肛门癌前病变的现有数据，并展示了证据空白和不确定性对一个临床决策模型的影响，该模型旨在为肛门癌前病变的管理提供临床指导。

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本文引用的文献

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Eurogin 2016 Roadmap: how HPV knowledge is changing screening practice.Eurogin 2016 路线图：HPV 知识如何改变筛查实践。
Int J Cancer. 2017 May 15;140(10):2192-2200. doi: 10.1002/ijc.30579. Epub 2017 Jan 11.
2
International trends in anal cancer incidence rates.国际肛门癌发病率趋势。
Int J Epidemiol. 2017 Jun 1;46(3):924-938. doi: 10.1093/ije/dyw276.
3
2016 IANS International Guidelines for Practice Standards in the Detection of Anal Cancer Precursors.2016年IANS肛管癌前病变检测实践标准国际指南。
J Low Genit Tract Dis. 2016 Oct;20(4):283-91. doi: 10.1097/LGT.0000000000000256.
4
Cumulative Incidence of Cancer Among Persons With HIV in North America: A Cohort Study.北美艾滋病毒感染者的癌症累积发病率：一项队列研究。
Ann Intern Med. 2015 Oct 6;163(7):507-18. doi: 10.7326/M14-2768.
5
Screening to prevent anal cancer: Current thinking and future directions.预防肛门癌的筛查：当前的思考与未来方向。
Cancer Cytopathol. 2015 Sep;123(9):509-10. doi: 10.1002/cncy.21571. Epub 2015 Aug 3.
6
Models in the development of clinical practice guidelines.临床实践指南制定中的模型。
Ann Intern Med. 2014 Dec 2;161(11):812-8. doi: 10.7326/M14-0845.
7
Communicating scientific uncertainty.传达科学的不确定性。
Proc Natl Acad Sci U S A. 2014 Sep 16;111 Suppl 4(Suppl 4):13664-71. doi: 10.1073/pnas.1317504111. Epub 2014 Sep 15.
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Who is ready to screen for anal squamous intraepithelial lesions and why should they perform high-resolution anoscopy?谁准备好筛查肛门鳞状上皮内病变，为什么他们应该进行高分辨率肛门镜检查？
Sex Transm Dis. 2014 Apr;41(4):254-6. doi: 10.1097/OLQ.0000000000000119.
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BMC Public Health. 2013 Oct 9;13:946. doi: 10.1186/1471-2458-13-946.