Dosik H, Denic S, Patel N, Krishnamurthy M, Levine P H, Clark J W
Department of Medicine, Interfaith Medical Center, Brooklyn, NY 11238.
JAMA. 1988 Apr 15;259(15):2255-7.
Fifteen patients with adult T-cell leukemia/lymphoma (ATLL) were identified in less than a two-year period in the Crown Heights-Bedford Stuyvesant section of Brooklyn, NY. All patients were black; nine patients originated from the Caribbean islands and six from the southern United States. Two of the patients were father and daughter, the first evidence of familial occurrence in the United States. Their clinical course was similar to that of previously described patients with this disorder. To our knowledge, these 15 patients represent the largest series of ATLL reported in the United States. We recommend that ATLL be seriously considered in the differential diagnosis of patients with non-Hodgkin's lymphoma, mycosis fungoides, lymphatic leukemia, or hypercalcemia.
在纽约布鲁克林皇冠高地-贝德福德-斯图维森特地区不到两年的时间里，确诊了15例成人T细胞白血病/淋巴瘤（ATLL）患者。所有患者均为黑人；9例患者来自加勒比群岛，6例来自美国南部。其中两名患者是父女，这是美国国内该疾病家族性发病的首个证据。他们的临床病程与先前描述的该疾病患者相似。据我们所知，这15例患者代表了美国报道的最大的ATLL病例系列。我们建议，在对非霍奇金淋巴瘤、蕈样肉芽肿、淋巴白血病或高钙血症患者进行鉴别诊断时，应认真考虑ATLL。
