青少年 HIV 感染者的烟草使用与持续病毒抑制。
Tobacco Use and Sustained Viral Suppression in Youth Living with HIV.
机构信息
Department of Health Behavior and Health Education, University of Michigan School of Public Health, 1415 Washington Heights, Ann Arbor, MI, 48109, USA.
Center for Sexuality and Health Disparities, University of Michigan, Ann Arbor, MI, USA.
出版信息
AIDS Behav. 2018 Jun;22(6):2018-2025. doi: 10.1007/s10461-017-1915-2.
Tobacco has been associated with worse HIV disease progression in adult samples of people living with HIV; however, studies have yet to examine these effects in youth living with HIV (YLWH). This study examined the association between tobacco smoking behaviors and sustained viral suppression among a sample of 820 YLWH who were recruited through the Adolescent Medicine Trials Network for HIV Interventions. Participants completed a cross-sectional survey and then staff abstracted viral suppression data from medical records for up to 26 weeks prior to enrollment. Overall, 20.4% of youth reported daily or almost daily tobacco use. In multivariable analyses, older age and daily or almost daily tobacco smoking, and ART adherence remained statistically significant in predicting sustained viral suppression over the study period. These findings underscore the need for tobacco screening and interventions in HIV care settings in order to identify youth in need of additional smoking cessation services.
烟草与成人 HIV 感染者的 HIV 疾病进展恶化相关；然而，这些影响在青少年 HIV 感染者（YLWH）中的研究尚少。本研究通过青少年医学试验网络 HIV 干预研究，招募了 820 名 YLWH 作为样本，检验了吸烟行为与该样本中持续病毒抑制之间的关系。参与者完成了一项横断面调查，然后工作人员从登记前最多 26 周的医疗记录中提取病毒抑制数据。总体而言，20.4%的青少年报告了每日或几乎每日吸烟。在多变量分析中，年龄较大、每日或几乎每日吸烟、ART 依从性在预测研究期间持续病毒抑制方面仍然具有统计学意义。这些发现强调了在 HIV 护理环境中进行烟草筛查和干预的必要性，以便发现需要额外戒烟服务的青少年。
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