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快速5分钟膝关节MRI协议与标准膝关节MRI协议的比较:一项多机构多阅片者研究。

Comparison of a fast 5-min knee MRI protocol with a standard knee MRI protocol: a multi-institutional multi-reader study.

作者信息

Alaia Erin FitzGerald, Benedick Alex, Obuchowski Nancy A, Polster Joshua M, Beltran Luis S, Schils Jean, Garwood Elisabeth, Burke Christopher J, Chang I-Yuan Joseph, Gyftopoulos Soterios, Subhas Naveen

机构信息

Department of Radiology, Musculoskeletal Division, NYU Langone Medical Center, New York, NY, USA.

School of Medicine, Case Western Reserve University, Cleveland, OH, USA.

出版信息

Skeletal Radiol. 2018 Jan;47(1):107-116. doi: 10.1007/s00256-017-2780-9. Epub 2017 Sep 26.

Abstract

PURPOSE

To compare diagnostic performance of a 5-min knee MRI protocol to that of a standard knee MRI.

MATERIALS AND METHODS

One hundred 3 T (100 patients, mean 38.8 years) and 50 1.5 T (46 patients, mean 46.4 years) MRIs, consisting of 5 fast, 2D multi-planar fast-spin-echo (FSE) sequences and five standard multiplanar FSE sequences, from two academic centers (1/2015-1/2016), were retrospectively reviewed by four musculoskeletal radiologists. Agreement between fast and standard (interprotocol agreement) and between standard (intraprotocol agreement) readings for meniscal, ligamentous, chondral, and bone pathology was compared for interchangeability. Frequency of major findings, sensitivity, and specificity was also tested for each protocol.

RESULTS

Interprotocol agreement using fast MRI was similar to intraprotocol agreement with standard MRI (83.0-99.5%), with no excess disagreement (≤ 1.2; 95% CI, -4.2 to 3.8%), across all structures. Frequency of major findings (1.1-22.4% across structures) on fast and standard MRI was not significantly different (p ≥ 0.215), except more ACL tears on fast MRI (p = 0.021) and more cartilage defects on standard MRI (p < 0.001). Sensitivities (59-100%) and specificities (73-99%) of fast and standard MRI were not significantly different for meniscal and ligament tears (95% CI for difference, -0.08-0.08). For cartilage defects, fast MRI was slightly less sensitive (95% CI for difference, -0.125 to -0.01) but slightly more specific (95% CI for difference, 0.01-0.5) than standard MRI.

CONCLUSION

A fast 5-min MRI protocol is interchangeable with and has similar accuracy to a standard knee MRI for evaluating internal derangement of the knee.

摘要

目的

比较5分钟膝关节MRI方案与标准膝关节MRI的诊断性能。

材料与方法

回顾性分析来自两个学术中心(2015年1月至2016年1月)的100例3T(100例患者,平均38.8岁)和50例1.5T(46例患者,平均46.4岁)的MRI图像,包括5个快速二维多平面快速自旋回波(FSE)序列和5个标准多平面FSE序列,由4名肌肉骨骼放射科医生进行分析。比较快速序列和标准序列(协议间一致性)以及标准序列(协议内一致性)在半月板、韧带、软骨和骨病变方面的读数一致性,以评估其互换性。同时测试每个方案的主要发现频率、敏感性和特异性。

结果

使用快速MRI的协议间一致性与使用标准MRI的协议内一致性相似(83.0 - 99.5%),在所有结构中无过多不一致(≤1.2;95%CI,-4.2至3.8%)。快速MRI和标准MRI上主要发现的频率(各结构为1.1 - 22.4%)无显著差异(p≥0.215),但快速MRI上前交叉韧带撕裂更多(p = 0.021),标准MRI上软骨缺损更多(p < 0.001)。对于半月板和韧带撕裂,快速MRI和标准MRI的敏感性(59 - 100%)和特异性(73 - 99%)无显著差异(差异的95%CI,-0.08至0.08)。对于软骨缺损,快速MRI的敏感性略低(差异的95%CI,-0.125至-0.01),但特异性略高(差异的95%CI,0.01至0.5)。

结论

对于评估膝关节内部紊乱,快速5分钟MRI方案与标准膝关节MRI具有互换性且准确性相似。

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