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围手术期整形手术中阿片类药物成瘾风险的管理

Managing Opioid Addiction Risk in Plastic Surgery during the Perioperative Period.

作者信息

Demsey Daniel, Carr Nicholas J, Clarke Hance, Vipler Sharon

机构信息

Vancouver, British Columbia; and Toronto, Ontario, Canada.

From the Division of Plastic Surgery and the Fraser Health Substance Use Services, University of British Columbia; and the Department of Anaesthesia and Pain Management, University of Toronto, Toronto General Hospital.

出版信息

Plast Reconstr Surg. 2017 Oct;140(4):613e-619e. doi: 10.1097/PRS.0000000000003742.

DOI:10.1097/PRS.0000000000003742
PMID:28953743
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5783634/
Abstract

Opioid addiction is a public health crisis that affects all areas of medicine. Large numbers of the population across all racial and economic demographics misuse prescription opioids and use illicit opioids. The current understanding is that opioid misuse is a disease that requires treatment, and is not an issue of choice or character. Use of opioid medication is a necessary part of postoperative analgesia, but many physicians are unsure of how to do this safely given the risk of patients developing an opioid misuse disorder. This review gives an update of the current state of the opioid crisis, explains how current surgeons' prescribing practices are contributing to it, and gives recommendations on how to use opioid medication safely in the perioperative period.

摘要

阿片类药物成瘾是一场影响医学各个领域的公共卫生危机。所有种族和经济层面的大量人群滥用处方阿片类药物并使用非法阿片类药物。目前的认识是,阿片类药物滥用是一种需要治疗的疾病,而非选择或性格问题。使用阿片类药物是术后镇痛的必要组成部分,但鉴于患者有发生阿片类药物滥用障碍的风险,许多医生不确定如何安全地做到这一点。本综述介绍了阿片类药物危机的当前状况,解释了当前外科医生的处方行为如何助长了这一危机,并就如何在围手术期安全使用阿片类药物给出了建议。

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Managing Opioid Addiction Risk in Plastic Surgery during the Perioperative Period.围手术期整形手术中阿片类药物成瘾风险的管理
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本文引用的文献

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Risk of Prolonged Opioid Use Among Opioid-Naïve Patients Following Common Hand Surgery Procedures.初次使用阿片类药物的患者在常见手部手术后长期使用阿片类药物的风险。
J Hand Surg Am. 2016 Oct;41(10):947-957.e3. doi: 10.1016/j.jhsa.2016.07.113. Epub 2016 Sep 28.
2
Unused opioid analgesics and drug disposal following outpatient dental surgery: A randomized controlled trial.门诊牙科手术后未使用的阿片类镇痛药及药物处置:一项随机对照试验。
Drug Alcohol Depend. 2016 Nov 1;168:328-334. doi: 10.1016/j.drugalcdep.2016.08.016. Epub 2016 Sep 20.
3
Risks of Developing Persistent Opioid Use After Major Surgery.
过去20年无阿片类麻醉的全球研究前沿与主题趋势:一项文献计量分析
Front Pharmacol. 2025 Apr 2;16:1562765. doi: 10.3389/fphar.2025.1562765. eCollection 2025.
4
Opioid prescribing patterns following surgical interventions for benign prostatic hyperplasia.良性前列腺增生手术干预后的阿片类药物处方模式。
Can Urol Assoc J. 2025 May;19(5):E160-E165. doi: 10.5489/cuaj.8958.
5
Ultrasonic- and Ultrasound-assisted Improvement of Silhouette of the Torso: Bone Structure High-definition Remodeling (Part I).超声及超声辅助改善躯干轮廓:骨骼结构高清重塑(第一部分)
Plast Reconstr Surg Glob Open. 2024 Jan 10;12(1):e5513. doi: 10.1097/GOX.0000000000005513. eCollection 2024 Jan.
6
Pain Medication Prescribing Patterns in Augmentation Mammoplasty.隆乳术中的止痛药物处方模式
Plast Surg (Oakv). 2023 Aug;31(3):270-274. doi: 10.1177/22925503211034828. Epub 2021 Oct 21.
7
Females Are More Likely Than Males to Fill an Opioid Prescription in the Year After Anterior Cruciate Ligament Reconstruction.在前交叉韧带重建术后的一年中,女性比男性更有可能开具阿片类药物处方。
Arthrosc Sports Med Rehabil. 2023 Jul 8;5(4):100758. doi: 10.1016/j.asmr.2023.100758. eCollection 2023 Aug.
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Multimodal Pain Control Reduces Narcotic Use after Outpatient Abdominoplasty: Retrospective Analysis in an Ambulatory Surgery Practice.多模式疼痛控制减少门诊腹部整形术后的麻醉药物使用:门诊手术实践中的回顾性分析
Plast Reconstr Surg Glob Open. 2023 Jan 23;11(1):e4777. doi: 10.1097/GOX.0000000000004777. eCollection 2023 Jan.
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Regional Pain Blocks and Perioperative Pain Control in Patients Undergoing Breast Implant Removal With Capsulectomy.接受乳房植入物取出并包膜切除术患者的区域疼痛阻滞与围手术期疼痛控制
Aesthet Surg J Open Forum. 2022 Oct 20;4:ojac079. doi: 10.1093/asjof/ojac079. eCollection 2022.
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Plast Reconstr Surg Glob Open. 2021 Aug 23;9(8):e3761. doi: 10.1097/GOX.0000000000003761. eCollection 2021 Aug.
大手术后发生持续性阿片类药物使用的风险。
JAMA Surg. 2016 Nov 1;151(11):1083-1084. doi: 10.1001/jamasurg.2016.1681.
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Preoperative Opioid Use is Independently Associated With Increased Costs and Worse Outcomes After Major Abdominal Surgery.术前使用阿片类药物与腹部大手术后成本增加及预后较差独立相关。
Ann Surg. 2017 Apr;265(4):695-701. doi: 10.1097/SLA.0000000000001901.
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Incidence of and Risk Factors for Chronic Opioid Use Among Opioid-Naive Patients in the Postoperative Period.术后初期未使用阿片类药物患者慢性阿片类药物使用的发生率及危险因素
JAMA Intern Med. 2016 Sep 1;176(9):1286-93. doi: 10.1001/jamainternmed.2016.3298.
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Opioids Prescribed After Low-Risk Surgical Procedures in the United States, 2004-2012.2004-2012 年美国低风险手术术后开阿片类药物处方的情况。
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Opioid Use and Storage Patterns by Patients after Hospital Discharge following Surgery.手术后出院患者的阿片类药物使用与储存模式
PLoS One. 2016 Jan 29;11(1):e0147972. doi: 10.1371/journal.pone.0147972. eCollection 2016.
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Increases in Drug and Opioid Overdose Deaths--United States, 2000-2014.药物和阿片类药物过量死亡人数增加 - 美国,2000-2014 年。
MMWR Morb Mortal Wkly Rep. 2016 Jan 1;64(50-51):1378-82. doi: 10.15585/mmwr.mm6450a3.