Witt Magdalena, Goniewicz Mariusz, Pawłowski Witold, Goniewicz Krzysztof, Biczysko Wiesława
Department of Rescue and Disaster Medicine, Poznan University of Medical Sciences, Poland.
Medical University of Lublin, Department of Emergency Medicine, Poland.
Ann Agric Environ Med. 2017 Sep 21;24(3):406-410. doi: 10.5604/12321966.1233561. Epub 2017 May 11.
Firefighters are considered a healthy and fit group of individuals, well-prepared for taking action in disaster situations. While working, they suffer from exposure to certain toxic agents, especially combustion products generated when a fire takes place. Among them, the most frequent and the most toxic are: carbon monoxide, hydrogen cyanide, ammonia, and those resulting from PVC combustion - hydrochloride, phosgene and chloride. Additionally, fire-extinguisher powder can be inhaled and lead to certain lesion in the airways. The aim of study was to ascertain the influence of toxic agents present at the scene of fire on the lung tissue of firefighters, and also to study this on an animal model.
The study group consisted of firefighters who had a minimum of 10 years service. After completing a questionnaire, their clinical status was ascertained based on a general examination, laboratory tests and lung function tests.
Questionnaire analysis showed a high percentage of pathological symptoms in the studied group. The incidence of the symptoms correlated with the duration of occupational exposure to toxic agents. Among other results, obstruction of flow in medium airways in about 30% of the studied individuals represented the most important finding. Experimental tests were next performed on male Wistar rats, aged 3 months. They were insufflated with the solution of powdered fire-extinguisher, after which morphology specimens of lung tissue were studied. Evidence for disseminated fibrosis was obtained, which supported the previous clinical findings in the firefighters.
The above shows correlation between occupational exposure and respiratory system involvement in firefighters. This justifies covering the group of firefighters with special medical care focused on prophilaxis, early detection and therapy of pulmonary diseases.
消防员被认为是一群健康且体能良好的人,为应对灾难情况做好了充分准备。在工作时,他们会接触到某些有毒物质,尤其是火灾发生时产生的燃烧产物。其中,最常见且毒性最大的有:一氧化碳、氰化氢、氨以及聚氯乙烯燃烧产生的物质——氯化氢、光气和氯气。此外,灭火器粉末可能被吸入并导致气道出现某些损伤。本研究的目的是确定火灾现场存在的有毒物质对消防员肺组织的影响,并在动物模型上进行研究。
研究组由至少有10年工作经验的消防员组成。完成问卷调查后,通过全身检查、实验室检测和肺功能测试确定他们的临床状况。
问卷调查分析显示,研究组中出现病理症状的比例很高。这些症状的发生率与职业接触有毒物质的时长相关。在其他结果中,约30%的研究对象中气道中气流受阻是最重要的发现。接下来对3个月大的雄性Wistar大鼠进行了实验测试。给它们吸入灭火器粉末溶液,之后对肺组织形态标本进行研究。获得了弥漫性纤维化的证据,这支持了之前在消防员身上的临床发现。
以上结果表明消防员的职业接触与呼吸系统受累之间存在关联。这证明应为消防员群体提供专门的医疗护理,重点是对肺部疾病的预防、早期检测和治疗。