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韩国学龄儿童碘摄入过量状况:首次报告

Excessive Iodine Status among School-Age Children in Korea: A First Report.

作者信息

Choi Young Sik, Ock Soyoung, Kwon Sukyoung, Jung Sang Bong, Seok Kwang Hyuk, Kim Young Jin, Kim Bu Kyung, Jeong Jee Yeong

机构信息

Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea.

Department Clinical Laboratory Science, Dong-Eui Institute of Technology, Busan, Korea.

出版信息

Endocrinol Metab (Seoul). 2017 Sep;32(3):370-374. doi: 10.3803/EnM.2017.32.3.370.

DOI:10.3803/EnM.2017.32.3.370
PMID:28956367
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5620034/
Abstract

BACKGROUND

Korea is considered an iodine sufficient country, and several studies have been conducted regarding iodine status in healthy Korean adults, pregnant women, and preschool children. However, data on iodine status in Korean school-age children are lacking. Therefore, the iodine nutrition status of Korean school-age children was investigated by measuring urine iodine concentration (UIC).

METHODS

This cross-sectional study conducted between April and September 2016 comprised 373 school-age children. UIC was determined using a modified microplate method employing ammonium persulfate digestion followed by Sandell-Kolthoff reaction.

RESULTS

The median UIC was 458.2 μg/L. Excessive iodine intake (>300 μg/L) was found in 286 children (76.7%), with extremely high values exceeding 1,000 μg/L in 19.6% of subjects. Insufficient iodine intake (<100 μg/L) was observed in eight children (2.1%). UIC values were not significantly different between sexes.

CONCLUSION

Korean school-age children showed excessive iodine intake. Therefore, education regarding adequate iodine intake in school-age children is needed.

摘要

背景

韩国被认为是一个碘充足的国家,并且已经针对韩国健康成年人、孕妇和学龄前儿童的碘状况开展了多项研究。然而,关于韩国学龄儿童碘状况的数据却很缺乏。因此,通过测量尿碘浓度(UIC)对韩国学龄儿童的碘营养状况进行了调查。

方法

这项于2016年4月至9月间开展的横断面研究纳入了373名学龄儿童。采用改良的微孔板法,用过硫酸铵消化后进行桑德尔-科尔托夫反应来测定尿碘浓度。

结果

尿碘浓度中位数为458.2μg/L。286名儿童(76.7%)存在碘摄入过量(>300μg/L)的情况,19.6%的受试者尿碘浓度极高,超过了1000μg/L。8名儿童(2.1%)存在碘摄入不足(<100μg/L)的情况。尿碘浓度值在性别之间无显著差异。

结论

韩国学龄儿童碘摄入过量。因此,需要对学龄儿童进行关于适量碘摄入的教育。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f851/5620034/74813d1141c6/enm-32-370-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f851/5620034/74813d1141c6/enm-32-370-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f851/5620034/74813d1141c6/enm-32-370-g001.jpg

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本文引用的文献

1
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2
Iodine deficiency and excess coexist in china and induce thyroid dysfunction and disease: a cross-sectional study.中国碘缺乏与碘过量并存,可导致甲状腺功能障碍和疾病:一项横断面研究。
PLoS One. 2014 Nov 6;9(11):e111937. doi: 10.1371/journal.pone.0111937. eCollection 2014.
3
Iodine and thyroid function.碘与甲状腺功能。
孕期和哺乳期母体碘状态对母体甲状腺功能及子代生长发育的影响:理想母乳队列前瞻性研究方案
Endocrinol Metab (Seoul). 2018 Sep;33(3):395-402. doi: 10.3803/EnM.2018.33.3.395.
4
Association between urinary sodium levels and iodine status in Korea.韩国人群尿钠水平与碘营养状况的关系。
Korean J Intern Med. 2020 Mar;35(2):392-399. doi: 10.3904/kjim.2017.375. Epub 2018 May 18.
Ann Pediatr Endocrinol Metab. 2014 Mar;19(1):8-12. doi: 10.6065/apem.2014.19.1.8. Epub 2014 Mar 31.
4
Long-term exposure to excessive iodine from water is associated with thyroid dysfunction in children.长期暴露于水中的过量碘与儿童甲状腺功能障碍有关。
J Nutr. 2013 Dec;143(12):2038-43. doi: 10.3945/jn.113.179135. Epub 2013 Oct 9.
5
Iodine status in Korean preschool children as determined by urinary iodine excretion.通过尿碘排泄量确定的韩国学龄前儿童的碘营养状况。
Eur J Nutr. 2014;53(2):683-8. doi: 10.1007/s00394-013-0558-y. Epub 2013 Jul 24.
6
Global iodine nutrition: Where do we stand in 2013?全球碘营养状况:2013 年我们处于什么位置?
Thyroid. 2013 May;23(5):523-8. doi: 10.1089/thy.2013.0128. Epub 2013 Apr 18.
7
Global iodine status in 2011 and trends over the past decade.2011 年全球碘状况及过去十年的变化趋势。
J Nutr. 2012 Apr;142(4):744-50. doi: 10.3945/jn.111.149393. Epub 2012 Feb 29.
8
Assessment of Japanese iodine intake based on seaweed consumption in Japan: A literature-based analysis.基于日本海藻消费情况的日本碘摄入量评估:一项基于文献的分析。
Thyroid Res. 2011 Oct 5;4:14. doi: 10.1186/1756-6614-4-14.
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10
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