韩国学龄儿童碘摄入过量状况：首次报告
Excessive Iodine Status among School-Age Children in Korea: A First Report.
作者信息
Choi Young Sik, Ock Soyoung, Kwon Sukyoung, Jung Sang Bong, Seok Kwang Hyuk, Kim Young Jin, Kim Bu Kyung, Jeong Jee Yeong
机构信息
Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea.
Department Clinical Laboratory Science, Dong-Eui Institute of Technology, Busan, Korea.
出版信息
Endocrinol Metab (Seoul). 2017 Sep;32(3):370-374. doi: 10.3803/EnM.2017.32.3.370.
BACKGROUND
Korea is considered an iodine sufficient country, and several studies have been conducted regarding iodine status in healthy Korean adults, pregnant women, and preschool children. However, data on iodine status in Korean school-age children are lacking. Therefore, the iodine nutrition status of Korean school-age children was investigated by measuring urine iodine concentration (UIC).
METHODS
This cross-sectional study conducted between April and September 2016 comprised 373 school-age children. UIC was determined using a modified microplate method employing ammonium persulfate digestion followed by Sandell-Kolthoff reaction.
RESULTS
The median UIC was 458.2 μg/L. Excessive iodine intake (>300 μg/L) was found in 286 children (76.7%), with extremely high values exceeding 1,000 μg/L in 19.6% of subjects. Insufficient iodine intake (<100 μg/L) was observed in eight children (2.1%). UIC values were not significantly different between sexes.
CONCLUSION
Korean school-age children showed excessive iodine intake. Therefore, education regarding adequate iodine intake in school-age children is needed.
背景
韩国被认为是一个碘充足的国家，并且已经针对韩国健康成年人、孕妇和学龄前儿童的碘状况开展了多项研究。然而，关于韩国学龄儿童碘状况的数据却很缺乏。因此，通过测量尿碘浓度（UIC）对韩国学龄儿童的碘营养状况进行了调查。
方法
这项于2016年4月至9月间开展的横断面研究纳入了373名学龄儿童。采用改良的微孔板法，用过硫酸铵消化后进行桑德尔-科尔托夫反应来测定尿碘浓度。
结果
尿碘浓度中位数为458.2μg/L。286名儿童（76.7%）存在碘摄入过量（>300μg/L）的情况，19.6%的受试者尿碘浓度极高，超过了1000μg/L。8名儿童（2.1%）存在碘摄入不足（<100μg/L）的情况。尿碘浓度值在性别之间无显著差异。
结论
韩国学龄儿童碘摄入过量。因此，需要对学龄儿童进行关于适量碘摄入的教育。
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