射波刀®系统：治疗鼻窦孤立性髓外浆细胞瘤的新策略。

Cyberknife® system: a new therapeutic strategy for sinonasal solitary extramedullary plasmacytomae.

作者信息

Cantone E, Borzillo V, Di Lullo A M, Marano L, Guadagno E, Mansueto G, Di Franco R, Cammarota F, Catalano L, Muto P, Iengo M

机构信息

Department of Neuroscience, ENT Section; “Federico II” University of Naples, Italy

Division of Radiotherapy, Istituto Nazionale Tumori Fondazione Pascale, Naples, Italy

出版信息

J Biol Regul Homeost Agents. 2017 Jul-Sep;31(3):763-768.

PMID:28958136

Abstract

Sino-nasal solitary extramedullary plasmacytoma (EMP) is a rare neoplasm with unpredictable progression to multiple myeloma. To improve the precision of irradiation delivery, preserving the healthy surrounding tissue and critical structures we used a CyberKnife® for the treatment of sinonasal solitary extramedullary plasmacytoma. We present the first case of sinonasal-EMP treated with CyberKnife®-stereotactic radiotherapy (SRT) with a complete remission without adverse events. Based on the post-therapeutic results and healthy tissue preservation, we believe that CyberKnife®-SRT represents a good therapeutic option for the treatment of sinonasal-EMP.

摘要

鼻窦孤立性髓外浆细胞瘤（EMP）是一种罕见肿瘤，其向多发性骨髓瘤进展的情况不可预测。为提高放疗的精准度，保护周围健康组织和关键结构，我们使用射波刀®治疗鼻窦孤立性髓外浆细胞瘤。我们报告首例采用射波刀®立体定向放射治疗（SRT）的鼻窦EMP病例，该病例实现完全缓解且无不良事件。基于治疗后的结果及对健康组织的保护，我们认为射波刀®SRT是治疗鼻窦EMP的一种良好治疗选择。