Department of Oncology, Çukurova University School of Medicine, Adana, Turkey.
Department of Pathology, Çukurova University School of Medicine, Adana, Turkey.
Balkan Med J. 2018 Mar 15;35(2):199-202. doi: 10.4274/balkanmedj.2017.0600. Epub 2017 Sep 29.
Thyroid cancer is the most common endocrine cancer, with an increasing incidence around the world in the last three decades. The increased risk of secondary cancer is associated with a genetic predisposition or radioactive iodine used in the treatment.
A 65-year old male patient was operated on for thyroid papillary cancer. He received radioactive iodine on two occasions postoperatively. After six years, he presented with malaise and fatigue with leukocytosis and eosinophlilia. The physical examination revealed inguinal lymphadenopathies and splenomegaly, after examining the bone marrow and lymph node biopsies, he was diagnosed with eosinophilic myeloproliferative neoplasia and T-cell lymphoblastic leukaemia/lymphoma.
Leukaemia and other haematological malignencies may develop after radioactive iodine treatment. Patients with radioactive iodine ablation history should be monitored for a long time.
甲状腺癌是最常见的内分泌癌,在过去三十年中,全球的发病率呈上升趋势。继发性癌症的风险增加与遗传易感性或治疗中使用放射性碘有关。
一名 65 岁男性患者因甲状腺乳头状癌接受手术治疗。他术后接受了两次放射性碘治疗。六年后,他出现不适和疲劳,伴有白细胞增多和嗜酸性粒细胞增多。体格检查显示腹股沟淋巴结病和脾肿大,骨髓和淋巴结活检后诊断为嗜酸性粒细胞髓系增生性肿瘤和 T 细胞淋巴母细胞白血病/淋巴瘤。
放射性碘治疗后可能会发生白血病和其他血液系统恶性肿瘤。接受放射性碘消融治疗的患者应长期监测。