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Myxedema Coma: A Forgotten Medical Emergency With a Precipitous Onset.黏液性水肿昏迷:一种起病急骤却被遗忘的医疗急症。
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本文引用的文献

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Hyponatremia and the Thyroid: Causality or Association?低钠血症与甲状腺:因果关系还是关联?
J Clin Med. 2014 Dec 26;4(1):32-6. doi: 10.3390/jcm4010032.
2
Myxedema coma: a sleeping giant in clinical practice.黏液性水肿昏迷:临床实践中的沉睡巨人。
Am J Med. 2013 Dec;126(12):e3-4. doi: 10.1016/j.amjmed.2013.07.037.
3
Clinical practice guidelines for hypothyroidism in adults: cosponsored by the American Association of Clinical Endocrinologists and the American Thyroid Association.成人甲状腺功能减退症临床实践指南:由美国临床内分泌医师学会和美国甲状腺协会共同赞助。
Endocr Pract. 2012 Nov-Dec;18(6):988-1028. doi: 10.4158/EP12280.GL.
4
The challenge of hyponatremia.低钠血症的挑战。
J Am Soc Nephrol. 2012 Jul;23(7):1140-8. doi: 10.1681/ASN.2012020128. Epub 2012 May 24.
5
Myxedema coma: a new look into an old crisis.黏液性水肿昏迷:对旧有危机的新审视。
J Thyroid Res. 2011;2011:493462. doi: 10.4061/2011/493462. Epub 2011 Sep 15.
6
The treatment of hyponatremia.低钠血症的治疗。
Semin Nephrol. 2009 May;29(3):282-99. doi: 10.1016/j.semnephrol.2009.03.002.
7
Predictors of outcome in myxoedema coma: a study from a tertiary care centre.黏液性水肿昏迷的预后预测因素:一项来自三级医疗中心的研究。
Crit Care. 2008;12(1):R1. doi: 10.1186/cc6211. Epub 2008 Jan 3.
8
Myxedema coma.黏液性水肿昏迷
Endocrinol Metab Clin North Am. 2006 Dec;35(4):687-98, vii-viii. doi: 10.1016/j.ecl.2006.09.003.
9
Factors associated with mortality of patients with myxoedema coma: prospective study in 11 cases treated in a single institution.黏液性水肿昏迷患者死亡率的相关因素:对一家机构治疗的11例患者的前瞻性研究。
J Endocrinol. 2004 Feb;180(2):347-50. doi: 10.1677/joe.0.1800347.
10
The pathophysiology and treatment of hyponatraemic encephalopathy: an update.低钠血症性脑病的病理生理学与治疗:最新进展
Nephrol Dial Transplant. 2003 Dec;18(12):2486-91. doi: 10.1093/ndt/gfg394.

加纳黏液水肿性昏迷患者管理中的挑战:一例报告

Challenges in the Management of a Patient with Myxoedema Coma in Ghana: A Case Report.

作者信息

Akpalu Josephine, Atiase Yacoba, Yorke Ernest, Fiscian Henrietta, Kootin-Sanwu Cecilia, Akpalu Albert

机构信息

Endocrinology Unit, Department of Medicine and Therapeutics, School of Medicine and Dentistry, College of Health Sciences, University of Ghana, P.O. Box GP 4236, Accra, Ghana.

Endocrinology Unit, Korle Bu Teaching Hospital, P.O. Box KB 77, Korle Bu.

出版信息

Ghana Med J. 2017 Mar;51(1):39-42. doi: 10.4314/gmj.v51i1.8.

DOI:10.4314/gmj.v51i1.8
PMID:28959072
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5611947/
Abstract

UNLABELLED

Myxoedema coma is a rare life-threatening disease, and it is essential that it is managed appropriately to reduce the associated high mortality. However, in the setting where efficient healthcare delivery is hampered by inadequacies, the management of such cases may pose a significant challenge. We present the case of a middle-aged woman diagnosed with myxoedema coma and severe hyponatremia. The case report highlights some of the challenges that may be encountered during the management of myxoedema coma in similar settings and outlines the management strategies undertaken to overcome them in the absence of national guidelines. It also brings to the fore the need for clinicians to look out for clinical features suggestive of hypothyroidism particularly among high risk individuals for early diagnosis and treatment.

FUNDING

None declared.

摘要

未标注

黏液性水肿昏迷是一种罕见的危及生命的疾病,必须进行适当管理以降低相关的高死亡率。然而,在医疗服务因不足而受阻的情况下,此类病例的管理可能构成重大挑战。我们报告一例诊断为黏液性水肿昏迷和严重低钠血症的中年女性病例。该病例报告强调了在类似情况下黏液性水肿昏迷管理过程中可能遇到的一些挑战,并概述了在缺乏国家指南的情况下为克服这些挑战而采取的管理策略。它还凸显了临床医生需要留意提示甲状腺功能减退的临床特征,尤其是在高危个体中以便早期诊断和治疗。

资金来源

未声明。