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感染的大疱性皮肤表现:病例系列

Bullous Skin Manifestations of Infection: A Case Series.

作者信息

Bhoopalan Senthil Velan, Chawla Vonita, Hogan Mary Beth, Wilson Nevin W, Das Samrat U

机构信息

University of Nevada, Las Vegas Campus, Las Vegas, NV, USA.

出版信息

J Investig Med High Impact Case Rep. 2017 Sep 8;5(3):2324709617727759. doi: 10.1177/2324709617727759. eCollection 2017 Jul-Sep.

DOI:10.1177/2324709617727759
PMID:28959692
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5593211/
Abstract

Bullous skin lesions are uncommon in children. While it is well known that infections are associated with papular skin manifestations, bullous skin lesions are not commonly reported. is a very common bacterial pathogen causing respiratory tract infection in children and adults. We report 2 children with serology-confirmed infection who were hospitalized for blistering skin lesions. Both of our patients responded well to corticosteroids and one of them required intravenous immunoglobulin. The aim of this case report is to raise awareness that infection can present with bullous skin lesions, and to briefly review the pathophysiology, diagnosis, and management of the skin manifestation of infection.

摘要

大疱性皮肤病变在儿童中并不常见。虽然众所周知感染与丘疹性皮肤表现有关,但大疱性皮肤病变并不常被报道。[病原体名称]是一种在儿童和成人中引起呼吸道感染的非常常见的细菌病原体。我们报告了2例血清学确诊[病原体名称]感染的儿童,他们因皮肤水疱性病变住院。我们的两名患者对皮质类固醇反应良好,其中一名患者需要静脉注射免疫球蛋白。本病例报告的目的是提高人们对[病原体名称]感染可出现大疱性皮肤病变的认识,并简要回顾[病原体名称]感染皮肤表现的病理生理学、诊断和管理。

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Bullous Skin Manifestations of Infection: A Case Series.感染的大疱性皮肤表现:病例系列
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Minerva Pediatr. 2008 Feb;60(1):135-9.
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本文引用的文献

1
Classification of Extrapulmonary Manifestations Due to Mycoplasma pneumoniae Infection on the Basis of Possible Pathogenesis.基于可能的发病机制对肺炎支原体感染所致肺外表现的分类
Front Microbiol. 2016 Jan 28;7:23. doi: 10.3389/fmicb.2016.00023. eCollection 2016.
2
Mycoplasma pneumoniae-induced rash and mucositis as a syndrome distinct from Stevens-Johnson syndrome and erythema multiforme: a systematic review.肺炎支原体感染相关性皮疹和黏膜炎综合征与史蒂文斯-约翰逊综合征和多形红斑的区别:系统评价。
J Am Acad Dermatol. 2015 Feb;72(2):239-45. doi: 10.1016/j.jaad.2014.06.026.
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Subcorneal pustular dermatosis triggered by Mycoplasma pneumoniae infection: a rare clinical association.肺炎支原体感染引发的角层下脓疱性皮肤病:一种罕见的临床关联。
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PCR versus serology for diagnosing Mycoplasma pneumoniae infection: a systematic review & meta-analysis.聚合酶链反应与血清学检测诊断肺炎支原体感染的比较:系统评价与荟萃分析。
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Review of intravenous immunoglobulin in the treatment of stevens-johnson syndrome and toxic epidermal necrolysis.静脉注射免疫球蛋白治疗史蒂文斯-约翰逊综合征和中毒性表皮坏死松解症的综述。
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Pathogenesis of extrapulmonary manifestations of Mycoplasma pneumoniae infection with special reference to pneumonia.肺炎支原体感染的肺外表现发病机制,特别是肺炎。
J Infect Chemother. 2010 Jun;16(3):162-9. doi: 10.1007/s10156-010-0044-x. Epub 2010 Feb 27.
7
Clinical, etiologic, and histopathologic features of Stevens-Johnson syndrome during an 8-year period at Mayo Clinic.8 年间 Mayo 诊所史蒂文斯-约翰逊综合征的临床、病因和组织病理学特征。
Mayo Clin Proc. 2010 Feb;85(2):131-8. doi: 10.4065/mcp.2009.0379.
8
Comparison of laboratory diagnostic procedures for detection of Mycoplasma pneumoniae in community outbreaks.社区爆发中检测肺炎支原体的实验室诊断程序比较
Clin Infect Dis. 2009 May 1;48(9):1244-9. doi: 10.1086/597775.
9
Erythema multiforme due to Mycoplasma pneumoniae infection in two children.两名儿童因肺炎支原体感染导致多形红斑。
Pediatr Dermatol. 2006 Nov-Dec;23(6):546-55. doi: 10.1111/j.1525-1470.2006.00307.x.
10
Pathogenesis and recent therapeutic trends in Stevens-Johnson syndrome and toxic epidermal necrolysis.史蒂文斯-约翰逊综合征和中毒性表皮坏死松解症的发病机制及近期治疗趋势
Ann Allergy Asthma Immunol. 2006 Sep;97(3):272-80; quiz 281-3, 320. doi: 10.1016/S1081-1206(10)60789-2.