Irwin M, Baird S, Smith T L, Schuckit M
Clinical Center for Research on Alcoholism, San Diego VA Medical Center, CA 92161.
Am J Psychiatry. 1988 May;145(5):595-9. doi: 10.1176/ajp.145.5.595.
Changes in blood test values from the time of discharge from an alcohol treatment program to 3-month follow-up were studied in two consecutive series of alcoholic men. The parallel combination of a percent increase in gamma-glutamyltransferase (GGT) of greater than or equal to 20%, in aspartate aminotransferase (SGOT) of greater than or equal to 40%, and in alanine aminotransferase (SGPT) of greater than or equal to 20% over discharge values was developed as a rule and then cross-validated to identify those alcoholic men who had resumed drinking at follow-up. Serial determination of these three test values in combination can be used to distinguish recovering alcoholics who remain abstinent from those who resume drinking.
在连续两组男性酒精依赖者中，研究了从酒精治疗项目出院时到3个月随访期间血液检测值的变化。制定了一项规则：γ-谷氨酰转移酶（GGT）较出院时升高大于或等于20%、天冬氨酸转氨酶（SGOT）升高大于或等于40%、丙氨酸转氨酶（SGPT）升高大于或等于20%这三者并行出现，并随后进行交叉验证，以识别那些在随访时已恢复饮酒的男性酒精依赖者。联合连续测定这三项检测值可用于区分仍保持戒酒的康复期酒精依赖者和已恢复饮酒的酒精依赖者。
