Hoffman S L, Edman D C, Punjabi N H, Lesmana M, Cholid A, Sundah S, Harahap J
Am J Trop Med Hyg. 1986 Jul;35(4):836-9. doi: 10.4269/ajtmh.1986.35.836.
We compared the sensitivities of bone marrow aspirate culture (BMAC), 3 ml 1:4 and 8 ml 1:10 blood-to-broth ratio blood cultures (BC), 8 ml streptokinase clot culture (STKCC) and rectal swab culture (RSC) for isolating Salmonella typhi and S. paratyphi A from 61 patients with typhoid or paratyphoid fever in Jakarta, Indonesia. BMAC (92%) was significantly more sensitive than 8 ml BC (62%), 8 ml STKCC (51%), 3 ml BC (44%), RSC (56%) and the 19 ml combination of all three BC methods (71%). The combination of the three BC methods and RSC had an isolation rate of 87%. In Jakarta the diagnosis of typhoid fever cannot be confidently excluded unless a BMAC is done.
我们比较了骨髓穿刺培养（BMAC）、3毫升血与肉汤比例为1:4和8毫升血与肉汤比例为1:10的血培养（BC）、8毫升链激酶凝块培养（STKCC）以及直肠拭子培养（RSC）从印度尼西亚雅加达61例伤寒或副伤寒热患者中分离伤寒沙门菌和甲型副伤寒沙门菌的敏感性。BMAC（92%）的敏感性显著高于8毫升血培养（62%）、8毫升链激酶凝块培养（51%）、3毫升血培养（44%）、直肠拭子培养（56%）以及三种血培养方法的19毫升联合培养（71%）。三种血培养方法与直肠拭子培养的联合培养分离率为87%。在雅加达，除非进行骨髓穿刺培养，否则不能轻易排除伤寒热的诊断。
