IEEE Trans Med Imaging. 2018 Jan;37(1):293-305. doi: 10.1109/TMI.2017.2756929. Epub 2017 Sep 26.
The use of appearance and shape priors in image segmentation is known to improve accuracy; however, existing techniques have several drawbacks. For instance, most active shape and appearance models require landmark points and assume unimodal shape and appearance distributions, and the level set representation does not support construction of local priors. In this paper, we present novel appearance and shape models for image segmentation based on a differentiable implicit parametric shape representation called a disjunctive normal shape model (DNSM). The DNSM is formed by the disjunction of polytopes, which themselves are formed by the conjunctions of half-spaces. The DNSM's parametric nature allows the use of powerful local prior statistics, and its implicit nature removes the need to use landmarks and easily handles topological changes. In a Bayesian inference framework, we model arbitrary shape and appearance distributions using nonparametric density estimations, at any local scale. The proposed local shape prior results in accurate segmentation even when very few training shapes are available, because the method generates a rich set of shape variations by locally combining training samples. We demonstrate the performance of the framework by applying it to both 2-D and 3-D data sets with emphasis on biomedical image segmentation applications.
基于可微分的显式参数形状表示——不连续正态形状模型(DNSM),我们提出了一种新颖的图像分割的外观和形状模型。DNSM 由多面体的不连续组成,而这些多面体本身又是由半空间的连接组成。DNSM 的参数特性允许使用强大的局部先验统计,其隐式特性消除了使用地标和轻松处理拓扑变化的需要。在贝叶斯推理框架中,我们使用非参数密度估计来模拟任意形状和外观分布,且在任何局部尺度上都可以使用。所提出的局部形状先验,即使在只有很少的训练形状可用的情况下,也能得到准确的分割,因为该方法通过局部组合训练样本生成了丰富的形状变化。我们通过将其应用于 2D 和 3D 数据集来展示框架的性能,重点是生物医学图像分割应用。