酵母细胞周期调控基因cdc2的人类同源基因的进化保守性及Cd2定位于10号染色体
Evolutionary conservation of the human homologue of the yeast cell cycle control gene cdc2 and assignment of Cd2 to chromosome 10.
作者信息
Spurr N K, Gough A, Goodfellow P J, Goodfellow P N, Lee M G, Nurse P
机构信息
Human Genetic Resources, Imperial Cancer Research Fund, Clare Hall Laboratories, South Mimms, Herts, UK.
出版信息
Hum Genet. 1988 Apr;78(4):333-7. doi: 10.1007/BF00291730.
PMID:2896153
Abstract
The human homologue of the fission yeast Schizosaccharomyces pombe cell cycle control gene cdc2 has been assigned to chromosome 10. DNA hybridization reveals that this gene is highly conserved in vertebrates. The human CDC2 gene probe detects a simple two-allele polymorphism in Taq1-digested DNA.
摘要
粟酒裂殖酵母细胞周期控制基因cdc2的人类同源基因已被定位于10号染色体。DNA杂交显示该基因在脊椎动物中高度保守。人类CDC2基因探针在经Taq1酶切的DNA中检测到一种简单的双等位基因多态性。
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