Xia Xiaoyu, Zhang Haoju, Gao Hongyan, Yang Yi, Dai Yiwu, Jiao Yang, He Jianghong
Department of Neurosurgery, PLA Army General Hospital, Beijing 100700, P.R. China.
Medical Administration Division, PLA Army General Hospital, Beijing 100700, P.R. China.
Exp Ther Med. 2017 Sep;14(3):2007-2014. doi: 10.3892/etm.2017.4780. Epub 2017 Jul 11.
The present study reported a nearly asymptomatic case of intracranial capillary hemangioma (ICHs), which are rare benign vascular tumors or tumor-like lesions. A 33-year-old female came to the hospital with a complaint of a slight but recurring morning headache concentrated in the left posterior occipital area. These headaches spontaneously resolved without any treatment. Computed tomography and magnetic resonance imaging revealed a mass inside the left occipital lobe. The patient refused to undergo conservative observation at home and insisted on radical therapy. Prior to surgery, an atypical meningioma or astrocytoma was suspected. A navigation-guided brain-mass resection was performed under general anesthesia and a solid mass closely associated with the tentorium cerebelli was completely resected. Histopathological analysis confirmed diagnosis of an ICH. The patient recovered well and experienced no major neurological defects, apart from an issue with the right visual field. The present study also conducted a retrospective literature review of papers published in English describing cases of intracranial capillary hemangiomas. A PubMed search identified 19 articles comprising 29 cases. The clinical symptoms of ICH are diverse and all reported cases in the literature were symptomatic. Previous studies demonstrated that diagnoses of intracranial capillary hemangioma are usually made during surgical resection by histopathological examination. Treatment for ICH remains empirical and surgery is the most common method of treatment. Patient prognosis is generally good-the majority of patients achieve long-term, event- and progression-free survival.
本研究报告了一例颅内毛细血管瘤（ICHs）的近乎无症状病例，颅内毛细血管瘤是罕见的良性血管肿瘤或肿瘤样病变。一名33岁女性因晨起后左侧枕后区域轻微但反复出现的头痛前来就医。这些头痛未经任何治疗便自行缓解。计算机断层扫描和磁共振成像显示左枕叶内有一个肿块。患者拒绝在家接受保守观察，坚持进行根治性治疗。手术前，怀疑为非典型脑膜瘤或星形细胞瘤。在全身麻醉下进行了导航引导下的脑肿块切除术，与小脑幕紧密相连的实性肿块被完全切除。组织病理学分析确诊为颅内毛细血管瘤。患者恢复良好，除了右视野出现问题外，没有出现重大神经功能缺损。本研究还对英文发表的描述颅内毛细血管瘤病例的论文进行了回顾性文献综述。通过PubMed搜索确定了19篇文章，共29例。颅内毛细血管瘤的临床症状多种多样，文献中报道的所有病例均有症状。先前的研究表明，颅内毛细血管瘤的诊断通常在手术切除时通过组织病理学检查做出。颅内毛细血管瘤的治疗仍基于经验，手术是最常见的治疗方法。患者预后通常良好——大多数患者实现了长期无事件和无进展生存。
