Carrara Mauro, Cutajar Dean, Alnaghy Saree, Espinoza Anthony, Romanyukha Anna, Presilla Stefano, Tenconi Chiara, Cerrotta Annamaria, Fallai Carlo, Safavi-Naeini Mitra, Petasecca Marco, Kejda Alannah, Lerch Michael, Corde Stéphanie, Jackson Michael, Howie Andrew, Bucci Joseph, Rosenfeld Anatoly B
Medical Physics Unit, Ente Ospedaliero Cantonale EOC, Bellinzona, Switzerland; Medical Physics Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.
Centre for Medical Radiation Physics, University of Wollongong, Wollongong, Australia; St. George Cancer Care Centre, St George Hospital, Kogarah, Australia.
Brachytherapy. 2018 Jan-Feb;17(1):133-145. doi: 10.1016/j.brachy.2017.08.013. Epub 2017 Sep 28.
With the increase in complexity of brachytherapy treatments, there has been a demand for the development of sophisticated devices for delivery verification. The Centre for Medical Radiation Physics (CMRP), University of Wollongong, has demonstrated the applicability of semiconductor devices to provide cost-effective real-time quality assurance for a wide range of brachytherapy treatment modalities. Semiconductor devices have shown great promise to the future of pretreatment and in vivo quality assurance in a wide range of brachytherapy treatments, from high-dose-rate (HDR) prostate procedures to eye plaque treatments. The aim of this article is to give an insight into several semiconductor-based dosimetry instruments developed by the CMRP. Applications of these instruments are provided for breast and rectal wall in vivo dosimetry in HDR brachytherapy, urethral in vivo dosimetry in prostate low-dose-rate (LDR) brachytherapy, quality assurance of HDR brachytherapy afterloaders, HDR pretreatment plan verification, and real-time verification of LDR and HDR source dwell positions.
随着近距离放射治疗复杂性的增加,对用于剂量验证的精密设备的需求也日益增长。卧龙岗大学医学辐射物理中心(CMRP)已证明,半导体设备可用于为多种近距离放射治疗方式提供经济高效的实时质量保证。从高剂量率(HDR)前列腺治疗到眼部敷贴治疗,半导体设备在广泛的近距离放射治疗的预处理和体内质量保证方面展现出了巨大的前景。本文旨在深入介绍CMRP研发的几种基于半导体的剂量测定仪器。这些仪器的应用包括HDR近距离放射治疗中乳腺和直肠壁的体内剂量测定、前列腺低剂量率(LDR)近距离放射治疗中尿道的体内剂量测定、HDR近距离放射治疗后装治疗机的质量保证、HDR预处理计划验证以及LDR和HDR源驻留位置的实时验证。