CJ CheilJedang Feed & Livestock Research Institute, Suwon 16495, Republic of Korea.
Biological and Genetic Resources Assessment Division, National Institute of Biological Resources, Incheon 22689, Republic of Korea.
J Glob Antimicrob Resist. 2017 Dec;11:108-110. doi: 10.1016/j.jgar.2017.09.013. Epub 2017 Sep 28.
This study aimed to determine the complete genome sequence of multidrug-resistant Staphylococcus sciuri strain SNUDS-18 isolated from a farmed duck in South Korea.
Genomic DNA was sequenced using a PacBio RS II system. The obtained genome was annotated and antimicrobial resistance and virulence genes were identified.
The sequenced genome possessed a mecA homologue (mecA1) that was almost identical to that of other oxacillin-susceptible S. sciuri strains, whereas the staphylococcal cassette chromosome mec (SCCmec) was not detected. Moreover, various antimicrobial resistance genes conferring resistance to β-lactams, aminoglycosides, phenicols, tetracycline and macrolide-lincosamide-streptogramin B (MLS) antimicrobials were identified.
The SNUDS-18 genome and its associated genomic data will provide important insights into the biodiversity of the S. sciuri group as well as valuable information for the control of this potential pathogen.
本研究旨在确定从韩国养殖场鸭中分离出的多药耐药松鼠葡萄球菌 SNUDS-18 菌株的全基因组序列。
使用 PacBio RS II 系统对基因组 DNA 进行测序。对获得的基因组进行注释，并鉴定了抗微生物药物耐药性和毒力基因。
测序的基因组含有 mecA 同源物（mecA1），与其他耐苯唑西林松鼠葡萄球菌菌株几乎完全相同，而未检测到葡萄球菌盒式染色体 mec（SCCmec）。此外，鉴定出了各种赋予对β-内酰胺类、氨基糖苷类、酚类、四环素类和大环内酯-林可酰胺-链阳菌素 B（MLS）类抗微生物药物耐药性的抗微生物药物耐药性基因。
SNUDS-18 基因组及其相关基因组数据将为了解松鼠葡萄球菌组的生物多样性提供重要信息，并为控制这种潜在病原体提供有价值的信息。
