Kwon Hyemin, Park Seon Young, Lee Seungki, Kim Sang Guen, Park Se Chang, Kim Ye Bin, Han Jee Eun, Kim Ji Hyung
Department of Microbiology and Molecular Biology, College of Bioscience and Biotechnology, Chungnam National University, Daejeon, 34134, Republic of Korea.
Division of Animal and Dairy Sciences, College of Agriculture and Life Science, Chungnam National University, Daejeon, 34134, Republic of Korea.
Arch Virol. 2023 Dec 11;169(1):4. doi: 10.1007/s00705-023-05940-1.
Mammaliicoccus sciuri is an opportunistic zoonotic pathogen in humans and animals. We isolated the Mammaliicoccus phage vB_MscM-PMS3, which was also able to infect and lyse M. sciuri and M. lentus. The phage genome is a linear dsDNA that is 147,811 bp in length and contains 206 ORFs and three tRNA genes. It showed low genome coverage (< 17%) and sequence identity (< 91.3%) to other phage genomes. Phylogenetic analysis based on the whole genome and major capsid protein revealed that this phage clustered with members of the subfamily Twortvirinae of the family Herelleviridae, but it was distinctly separated from the other members, indicating its uniqueness.
松鼠哺乳动物球菌是人和动物中的一种机会性人畜共患病原体。我们分离出了松鼠哺乳动物噬菌体vB_MscM-PMS3，它也能够感染并裂解松鼠哺乳动物球菌和迟缓哺乳动物球菌。该噬菌体基因组是一条线性双链DNA，长度为147,811 bp，包含206个开放阅读框和三个tRNA基因。它与其他噬菌体基因组的基因组覆盖率较低（<17%），序列同一性也较低（<91.3%）。基于全基因组和主要衣壳蛋白的系统发育分析表明，该噬菌体与赫勒病毒科Twortvirinae亚科的成员聚集在一起，但与其他成员明显分开，表明其独特性。
