Sturrock Andrew, Preshaw Philip M, Hayes Catherine, Wilkes Scott
Faculty of Health Sciences and Wellbeing, University of Sunderland, Sunderland, UK.
Centre for Oral Health Research and Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, Tyne and Wear, UK.
BMJ Open. 2017 Sep 29;7(9):e016047. doi: 10.1136/bmjopen-2017-016047.
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a rare, yet significant, adverse effect of bisphosphonate therapy. A multidisciplinary approach to the prevention of BRONJ is recommended due to the significant morbidity and difficulty treating the condition. Current evidence suggests that both general practitioners (GPs) and community pharmacists have limited knowledge relating to BRONJ and that preventative strategies are rarely implemented.
To explore the attitudes and perceptions of GPs and community pharmacists on the risks and preventative strategies for the development of BRONJ.
Interpretivist methodological approach using qualitative semistructured interviews.
9 community pharmacists and 8 GPs.
Primary Care in North East England and Cumbria, UK.
Using a Grounded Theory methodology and integrating a process of constant comparison in the iterative enrichment of data sets, semistructured interviews were undertaken, transcribed and analysed using framework analysis. Salient themes were identified and related back to extant literature in the field.
Four salient and inter-related themes emerged: (1) uncertain knowledge, indicating limited exposure of respondents to BRONJ, and limited awareness of the implications of its diagnosis, risk factors and preventative strategies; (2) patient specific, referring to the complexity of patients, patient education and prioritising aspects of care; (3) wider context, indicating a lack of interdisciplinary communication and referral processes between professions, workload pressures, access and patient receptivity to dental services; and (4) professional, reflecting professional roles and responsibilities, authority and educational initiatives CONCLUSIONS: Effective communication or collaborative care between GPs and community pharmacists for the prevention of BRONJ is not apparent. Interventions to mitigate against the risk of developing BRONJ and clarity of GP and community pharmacy roles are required.
双膦酸盐相关颌骨坏死(BRONJ)是双膦酸盐治疗罕见但严重的不良反应。鉴于该病症的高发病率及治疗难度,推荐采用多学科方法预防BRONJ。目前证据表明,全科医生(GPs)和社区药剂师对BRONJ的了解有限,预防策略也很少实施。
探讨全科医生和社区药剂师对BRONJ发生风险及预防策略的态度和看法。
采用定性半结构化访谈的解释主义方法论。
9名社区药剂师和8名全科医生。
英国英格兰东北部和坎布里亚郡的初级医疗服务机构。
采用扎根理论方法,在数据集的迭代丰富过程中整合持续比较的过程,进行半结构化访谈,转录并使用框架分析进行分析。确定突出主题并与该领域现有文献相关联。
出现了四个突出且相互关联的主题:(1)知识不确定,表明受访者对BRONJ的接触有限,对其诊断、风险因素和预防策略的影响认识不足;(2)患者特异性,指患者的复杂性、患者教育以及护理方面的优先级;(3)更广泛的背景,表明各专业之间缺乏跨学科沟通和转诊流程、工作量压力、获得牙科服务的机会以及患者对牙科服务的接受度;(4)专业方面,反映专业角色和职责、权威及教育举措。结论:全科医生和社区药剂师之间为预防BRONJ而进行的有效沟通或协作护理并不明显。需要采取干预措施以降低发生BRONJ的风险,并明确全科医生和社区药房的角色。