Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.
School of Nursing, Oregon Health & Science University, Mailcode: SN-ORD, 3455 SW US Veteran's Hospital Road, Portland, OR, 97239, USA.
Support Care Cancer. 2018 Mar;26(3):905-912. doi: 10.1007/s00520-017-3909-z. Epub 2017 Sep 30.
Fatigue is a troublesome symptom for breast cancer patients, which might be mitigated with exercise. Cancer patients often prefer their oncologist recommend an exercise program, yet a recommendation alone may not be enough to change behavior. Our study determined whether adding an exercise DVD to an oncologist's recommendation to exercise led to better outcomes than a recommendation alone.
Ninety breast cancer patients, at varying phases of treatment and stages of disease, were randomized to receive the following: an oncologist verbal recommendation to exercise (REC; n = 43) or REC plus a cancer-specific yoga DVD (REC + DVD; n = 47). Fatigue, vigor, and depression subscales of the Profile of Mood States, and physical activity levels (MET-min/week), exercise readiness, and self-efficacy were assessed at baseline, 4, and 8 weeks. Analyses controlled for age, time since diagnosis, and metastatic disease.
Over 8 weeks, women in REC + DVD used the DVD an average of twice per week. The REC + DVD group had greater reductions in fatigue (- 1.9 ± 5.0 vs. - 1.0 ± 3.5, p = 0.02), maintained exercise readiness (- 0.1 ± 1.1 vs. - 0.3 ± 1.3; p = 0.03), and reported less of a decrease in physical activity (- 420 ± 3075 vs. - 427 ± 5060 MET-min/week, p = 0.06) compared to REC only.
A low-cost, easily distributed, and scalable yoga-based DVD could be a simple booster to an oncologist's advice that motivates breast cancer patients, even those with advanced disease and/or in treatment, to engage in self-care, e.g., exercise, to manage fatigue.
ClinicalTrials.gov Identifier: NCT03120819.
疲劳是乳腺癌患者的一个麻烦症状，可以通过运动来缓解。癌症患者通常希望他们的肿瘤医生推荐一个锻炼计划，但仅仅推荐可能不足以改变行为。我们的研究旨在确定在肿瘤医生推荐锻炼的基础上增加锻炼 DVD 是否比仅推荐锻炼更能带来更好的结果。
90 名处于不同治疗阶段和疾病阶段的乳腺癌患者被随机分为以下两组：接受肿瘤医生口头推荐锻炼（REC；n=43）或 REC 加癌症特异性瑜伽 DVD（REC+DVD；n=47）。在基线、4 周和 8 周时，评估了心境状态问卷疲劳、活力和抑郁分量表以及身体活动水平（MET-min/周）、运动准备度和自我效能。分析控制了年龄、诊断后时间和转移性疾病。
在 8 周内，REC+DVD 组的女性平均每周使用 DVD 两次。与 REC 组相比，REC+DVD 组的疲劳感降低更为明显（-1.9±5.0 与-1.0±3.5，p=0.02），运动准备度保持更好（-0.1±1.1 与-0.3±1.3；p=0.03），并且报告的身体活动减少量较小（-420±3075 与-427±5060 MET-min/周，p=0.06）。
一种低成本、易于分发和可扩展的基于瑜伽的 DVD 可以作为肿瘤医生建议的简单助推器，激励乳腺癌患者，即使是患有晚期疾病和/或正在接受治疗的患者，也可以进行自我保健，例如运动，以缓解疲劳。
ClinicalTrials.gov 标识符：NCT03120819。
