Department of Medicine, Holbæk Hospital, 4300, Holbæk, Denmark.
Department of Clinical Research, Odense Patient Data Explorative Network, University of Southern Denmark, 5000, Odense, Denmark.
Osteoporos Int. 2018 Jan;29(1):109-114. doi: 10.1007/s00198-017-4247-1. Epub 2017 Sep 30.
Fracture liaison services prevent hip fractures by identifying other osteoporotic fractures that generally debut at a younger age. However, this study showed that a minority of hip fracture patients are already known to the health services through having had prior osteoporotic fractures. Identification of vertebral fractures in particular is lacking.
The purpose of this study was to examine the prevalence of prior major osteoporotic fractures (MOF) in the prior 10 years preceding hip fracture in order to provide information about the potential for prevention of hip fractures by fracture liaison services (FLS).
We included all patients aged 50+ with surgically treated hip fracture in one calendar year (N = 8158) in the Danish Hospital Discharge Register. Prior fractures were identified using the same data source. A prior hip fracture was only included as a prior fracture if occurring more than 6 months before the present fracture.
A total of 28% of hip fracture patients (32% of women and 19% of men) had at least one recognized MOF in the preceding 10 years. Forearm and humerus fractures constituted > 70% of prior MOF. In both genders, vertebral fractures only represented a small percentage (2.6%) of previously recognized MOF. Men were less likely than women to have experienced a prior MOF, chiefly due to fewer forearm and humerus fractures.
The majority of hip fractures-and in particular hip fractures in men-occur without a previously treated MOF that could have resulted in early detection and treatment of osteoporosis. With current treatment modalities, a maximum of one in six hip fractures in Denmark can be prevented through FLS initiatives. Identification of patients with vertebral fractures for assessment and treatment is therefore critical for successful prevention of hip fractures using this strategy.
骨折联络服务通过识别通常出现在更年轻年龄的其他骨质疏松性骨折来预防髋部骨折。然而,这项研究表明,少数髋部骨折患者已经通过先前的骨质疏松性骨折而被卫生服务机构所知晓。特别是椎体骨折的识别存在不足。
本研究的目的是检查在髋部骨折前 10 年内先前发生的主要骨质疏松性骨折(MOF)的患病率,以便为通过骨折联络服务(FLS)预防髋部骨折提供信息。
我们将丹麦住院患者登记处中某一年(N=8158)接受手术治疗的所有 50 岁以上髋部骨折患者纳入研究。先前的骨折通过相同的数据来源确定。先前的髋部骨折仅在当前骨折前 6 个月以上发生时才被视为先前骨折。
共有 28%的髋部骨折患者(女性为 32%,男性为 19%)在过去 10 年内至少有一次已识别的 MOF。前臂和肱骨骨折占先前 MOF 的>70%。在两性中,椎体骨折仅占先前已识别的 MOF 的一小部分(2.6%)。男性发生先前 MOF 的可能性低于女性,主要是由于前臂和肱骨骨折较少。
大多数髋部骨折,特别是男性的髋部骨折,发生时没有先前治疗过的 MOF,这可能导致骨质疏松症的早期发现和治疗。通过当前的治疗方式,丹麦最多有六分之一的髋部骨折可以通过 FLS 计划预防。因此,对于使用这种策略成功预防髋部骨折,识别出患有椎体骨折的患者进行评估和治疗至关重要。