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高生物利用度格拉非宁与对乙酰氨基酚治疗颈腰椎关节病的对比研究

Comparative study of high bio-availability glaphenine and paracetamol in cervical and lumbar arthrosis.

作者信息

Urbin Choffray D, Crielaard J M, Albert A, Franchimont P

机构信息

Department of Rheumatology, University Hospital of Liège, Belgium.

出版信息

Clin Rheumatol. 1987 Dec;6(4):518-25. doi: 10.1007/BF02330588.

Abstract

Seventy-eight patients, 40 suffering from cervical arthrosis and 38 from lumbar arthrosis, received for a period of two weeks paracetamol or a new preparation of glaphenine, in a double blind study. The two drugs were found to have the same efficiency on the subjective parameters but high bioavailability glaphenine seems to have an effectiveness in the range of articulatory movements, which is not found with paracetamol. The side effects were quite equivalent.

摘要

在一项双盲研究中,78名患者(40名患有颈椎病,38名患有腰椎病)接受了为期两周的扑热息痛或一种新的格拉非宁制剂治疗。结果发现,两种药物在主观参数上具有相同的疗效,但高生物利用度的格拉非宁在关节活动范围内似乎具有扑热息痛所没有的有效性。副作用相当。

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