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高生物利用度格拉非宁与对乙酰氨基酚治疗颈腰椎关节病的对比研究

Comparative study of high bio-availability glaphenine and paracetamol in cervical and lumbar arthrosis.

作者信息

Urbin Choffray D, Crielaard J M, Albert A, Franchimont P

机构信息

Department of Rheumatology, University Hospital of Liège, Belgium.

出版信息

Clin Rheumatol. 1987 Dec;6(4):518-25. doi: 10.1007/BF02330588.

DOI:10.1007/BF02330588
PMID:2896557
Abstract

Seventy-eight patients, 40 suffering from cervical arthrosis and 38 from lumbar arthrosis, received for a period of two weeks paracetamol or a new preparation of glaphenine, in a double blind study. The two drugs were found to have the same efficiency on the subjective parameters but high bioavailability glaphenine seems to have an effectiveness in the range of articulatory movements, which is not found with paracetamol. The side effects were quite equivalent.

摘要

在一项双盲研究中,78名患者(40名患有颈椎病,38名患有腰椎病)接受了为期两周的扑热息痛或一种新的格拉非宁制剂治疗。结果发现,两种药物在主观参数上具有相同的疗效,但高生物利用度的格拉非宁在关节活动范围内似乎具有扑热息痛所没有的有效性。副作用相当。

相似文献

1
Comparative study of high bio-availability glaphenine and paracetamol in cervical and lumbar arthrosis.高生物利用度格拉非宁与对乙酰氨基酚治疗颈腰椎关节病的对比研究
Clin Rheumatol. 1987 Dec;6(4):518-25. doi: 10.1007/BF02330588.
2
Tiapride versus glafenine: a double-blind comparative study in the management of acute rheumatic pain.硫必利与格拉非宁:急性风湿性疼痛治疗的双盲对照研究
Curr Med Res Opin. 1983;8(8):562-9. doi: 10.1185/03007998309109799.
3
[Effectiveness of high-bioavailability glafenine tablets in stomatology. Double-blind comparison with standard glaphenine in post-apicoectomy pain (wisdom teeth included)].[高生物利用度格拉非宁片在口腔医学中的有效性。与标准格拉非宁在根尖切除术后疼痛(包括智齿)方面的双盲比较]
Bull Group Int Rech Sci Stomatol Odontol. 1984 Jul;27(3):199-205.
4
A method for comparing analgesics: glafenine and paracetamol. Multicenter cross-over approach.一种比较镇痛药的方法:格拉非宁与对乙酰氨基酚。多中心交叉研究方法。
Clin Rheumatol. 1988 Dec;7(4):492-7.
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Comparative analgesic efficacy and tolerability of ketorolac tromethamine and glafenine in patients with post-operative pain.酮咯酸氨丁三醇与格拉非宁对术后疼痛患者的镇痛效果及耐受性比较
Curr Med Res Opin. 1988;11(4):214-20. doi: 10.1185/03007998809114238.
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[Efficacy and tolerance of dolo/tanderil capsules in arthrosis of the knee].多洛/坦德瑞尔胶囊治疗膝关节骨性关节炎的疗效与耐受性
Rev Esp Reum Enferm Osteoartic. 1980;23(2):95-111.
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[Hepatitis induced by glaphenine].[格拉非宁所致肝炎]
Therapie. 1982 May-Jun;37(3):327-8.
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A double-blind comparative clinical trial of floctafenine and four other analgesics conducted in general practice.在普通医疗实践中进行的氟考芬那酯与其他四种镇痛药的双盲对照临床试验。
J Int Med Res. 1976;4(3):179-82. doi: 10.1177/030006057600400306.
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[Liver damage following taking of glaphenine].服用格拉非宁后出现的肝损伤
Ned Tijdschr Geneeskd. 1979 Dec 22;123(51):2193-4.
10
[Acute yellow atrophy following taking of glaphenine].服用格拉非宁后发生的急性黄色肝萎缩
Ned Tijdschr Geneeskd. 1979 Oct 13;123(41):1800.

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Efficacy and safety of diclofenac diethylamine 1.16% gel in acute neck pain: a randomized, double-blind, placebo-controlled study.双氯芬酸二乙胺 1.16%凝胶治疗急性颈痛的疗效和安全性:一项随机、双盲、安慰剂对照研究。
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本文引用的文献

1
[Effectiveness of high-bioavailability glafenine tablets in stomatology. Double-blind comparison with standard glaphenine in post-apicoectomy pain (wisdom teeth included)].[高生物利用度格拉非宁片在口腔医学中的有效性。与标准格拉非宁在根尖切除术后疼痛(包括智齿)方面的双盲比较]
Bull Group Int Rech Sci Stomatol Odontol. 1984 Jul;27(3):199-205.
2
The use of glifanan in postoperative pain.格列凡南在术后疼痛中的应用。
S Afr Med J. 1971 Nov 6;45(43):1235-7.
3
A comparison of the analgesic effectiveness of glaphenine and standard oral analgesics in postoperative orthopedic patients.
J Clin Pharmacol New Drugs. 1971 Sep-Oct;11(5):378-82.
4
A controlled trial of glifanan and omnopon in postoperative pain.关于格列凡南和阿片全碱用于术后疼痛的对照试验。
S Afr Med J. 1971 Feb 20;45(8):203-5.
5
[Pain relief with simple analgesics in dentistry].[牙科中使用简单镇痛药缓解疼痛]
Ned Tijdschr Tandheelkd. 1972 Feb;79(2):69-75.