Heydari Gholamreza
Tobacco Prevention and Control Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Int J Prev Med. 2017 Aug 31;8:63. doi: 10.4103/ijpvm.IJPVM_375_16. eCollection 2017.
Providing smoking cessation services are special importance to tobacco control programs. To date, Champix is a new expensive medication for smoking cessation available nationally. Champix has both agonist and antagonist activities and can reduce nicotine dependence and withdrawal symptoms. The purpose of this study was to evaluate the duration of using Champix based on its cost.
This quasi-experimental study was conducted with smokers presenting to the Tanaffos Smoking Cessation Clinic in Tehran, Iran 2016. Smokers were visited by a physician 3 times at 1-week intervals for counseling. Smokers started to use Champix and stopped smoking in the 2nd week of counseling and were followed up by phone and through regular visits to the clinic at 1, 3, and 6 months postintervention. Some of them did not continue medication for 12 weeks because of its cost.
A total of 227 smokers including 133 males (58%) with a mean age of 43 years were enrolled of whom 116 (51.1%), 89 (43.6%), and 34 (20.6%) had quit smoking after 1, 3, and 6 months, respectively. Quit rates were significantly higher among those who used Champix for more than 6 weeks, and this rate was not correlated with age, sex, educational level, or nicotine dependence.
Use of Champix for more than 6 weeks increases the quitting success rate compared with using for a shorter time. The cost of Champix was important for smokers and adding Champix to the list of insurance medication or getting it free of charge is needed.
提供戒烟服务对烟草控制项目尤为重要。迄今为止，畅沛是一种在全国范围内可获得的新型昂贵戒烟药物。畅沛具有激动剂和拮抗剂活性，可减轻尼古丁依赖和戒断症状。本研究的目的是根据成本评估使用畅沛的时长。
本准实验研究于2016年在伊朗德黑兰的塔纳福斯戒烟诊所对吸烟者进行。医生每隔1周对吸烟者进行3次访视以提供咨询。吸烟者在咨询的第2周开始使用畅沛并戒烟，在干预后1、3和6个月通过电话及定期到诊所随访。他们中的一些人因成本问题未持续用药12周。
共纳入227名吸烟者，其中133名男性（58%），平均年龄43岁，分别有116名（51.1%）、89名（43.6%）和34名（20.6%）在1、3和6个月后戒烟。使用畅沛超过6周者的戒烟率显著更高，且该率与年龄、性别、教育水平或尼古丁依赖无关。
与较短时间使用相比，使用畅沛超过6周可提高戒烟成功率。畅沛的成本对吸烟者很重要，需要将畅沛列入保险药物清单或免费提供。
