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众包促进中国男男性行为者的艾滋病毒检测:一项阶梯式楔形随机对照试验的研究方案

Crowdsourcing to promote HIV testing among MSM in China: study protocol for a stepped wedge randomized controlled trial.

作者信息

Tucker Joseph D

机构信息

University of North Carolina Chapel Hill Project-China, No. 2 Lujing Road, Guangzhou, 510095, China.

出版信息

Trials. 2017 Oct 2;18(1):447. doi: 10.1186/s13063-017-2183-1.

Abstract

BACKGROUND

HIV testing for marginalized populations is critical to controlling the HIV epidemic. However, the HIV testing rate among men who have sex with men (MSM) in China remains low. Crowdsourcing, the process of shifting individual tasks to a group, has been increasingly adopted in public health programs and may be a useful tool for spurring innovation in HIV testing campaigns. We designed a multi-site study to develop a crowdsourced HIV test promotion campaign and evaluate its effectiveness against conventional campaigns among MSM in China.

METHODS

This study will use an adaptation of the stepped wedge, randomized controlled trial design. A total of eight major metropolitan cities in China will be randomized to sequentially initiate interventions at 3-month intervals. The intervention uses crowdsourcing at multiple steps to sustain crowd contribution. Approximately 1280 MSM, who are 16 years of age or over, live in the intervention city, have not been tested for HIV in the past 3 months, and are not living with HIV, will be recruited. Recruitment will take place through banner advertisements on a large gay dating app along with other social media platforms. Participants will complete one follow-up survey every 3 months for 12 months to evaluate their HIV testing uptake in the past 3 months and secondary outcomes including syphilis testing, sex without condoms, community engagement, testing stigma, and other related outcomes.

DISCUSSION

MSM HIV testing rates remain poor in China. Innovative methods to promote HIV testing are urgently needed. With a large-scale, stepped wedge, randomized controlled trial our study can improve understanding of crowdsourcing's long-term effectiveness in public health campaigns, expand HIV testing coverage among a key population, and inform intervention design in related public health fields.

TRIAL REGISTRATION

ClinicalTrials.gov, NCT02796963 . Registered on 23 May 2016.

摘要

背景

对边缘化人群进行艾滋病毒检测对于控制艾滋病毒流行至关重要。然而,中国男男性行为者(MSM)中的艾滋病毒检测率仍然很低。众包,即将个体任务转移到群体的过程,已越来越多地应用于公共卫生项目中,可能是推动艾滋病毒检测活动创新的有用工具。我们设计了一项多地点研究,以开展一项众包的艾滋病毒检测促进活动,并评估其在中国男男性行为者中相对于传统活动的有效性。

方法

本研究将采用改良的阶梯楔形随机对照试验设计。中国总共八个主要大城市将被随机分组,以每隔3个月依次启动干预措施。该干预措施在多个步骤中采用众包方式以维持群体参与度。将招募约1280名年龄在16岁及以上、居住在干预城市、在过去3个月内未进行过艾滋病毒检测且未感染艾滋病毒的男男性行为者。招募将通过一个大型同性恋交友应用程序上的横幅广告以及其他社交媒体平台进行。参与者将在12个月内每3个月完成一次随访调查,以评估他们在过去3个月内的艾滋病毒检测接受情况以及包括梅毒检测、无保护性行为、社区参与、检测耻辱感和其他相关结果在内的次要结果。

讨论

中国男男性行为者的艾滋病毒检测率仍然很低。迫切需要创新的方法来促进艾滋病毒检测。通过一项大规模的阶梯楔形随机对照试验,我们的研究可以增进对众包在公共卫生活动中的长期有效性的理解,扩大关键人群中的艾滋病毒检测覆盖范围,并为相关公共卫生领域的干预设计提供信息。

试验注册

ClinicalTrials.gov,NCT02796963。于2016年5月23日注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce66/5625620/2bb3bf96030c/13063_2017_2183_Fig1_HTML.jpg

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