Kumar Ajay, Neema Praveen Kumar
Department of Anaesthesiology, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India.
Indian J Anaesth. 2017 Sep;61(9):753-759. doi: 10.4103/ija.IJA_420_17.
Perioperative management of severe pulmonary hypertension (PH) is challenging. Anaesthesiologists come across perioperative management of such cases during incidental surgeries, surgery for various congenital heart diseases and valvular heart diseases and for caesarean section or painless labour in pregnant patient with Eisenmenger syndrome. Knowledge of pathophysiology of PH and novel drugs acting through different mechanisms is paramount in managing such patients. This review will help understanding pathophysiology of PH, anaesthetising patients with PH, use of novel drugs for PH and use of new mechanical devices for rescue of failing right ventricle.
重度肺动脉高压(PH)的围手术期管理具有挑战性。麻醉医生在进行择期手术、各种先天性心脏病和心脏瓣膜病手术以及患有艾森曼格综合征的孕妇进行剖宫产或无痛分娩时,会遇到此类病例的围手术期管理问题。了解PH的病理生理学以及通过不同机制起作用的新型药物,对于管理此类患者至关重要。这篇综述将有助于理解PH的病理生理学、为PH患者实施麻醉、使用治疗PH的新型药物以及使用新的机械装置挽救衰竭的右心室。