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经闭孔吊带治疗前列腺切除术后尿失禁:放疗对疗效/满意度的影响

Transobturator sling for post-prostatectomy incontinence: radiation's effect on efficacy/satisfaction.

作者信息

Wright Henry C, McGeagh Kevin, Richter Lee A, Hwang Jonathan J, Venkatesan Krishnan, Pysher Amanda, Koch George E, Kowalczyk Keith, Bandi Gaurav, Marchalik Daniel

机构信息

Department of Urology, MedStar Georgetown University Hospital, Washington, DC, USA.

出版信息

Can J Urol. 2017 Oct;24(5):8998-9002.

Abstract

INTRODUCTION

We review our experience with the AdVance sling in patients with post- prostatectomy incontinence, comparing the role that adjuvant radiation therapy plays in sling success and patient satisfaction at short and long term follow ups.

MATERIALS AND METHODS

Men who underwent AdVance sling placement for post-prostatectomy incontinence from 2007 to present were identified using Current Procedural Terminology (CPT) codes. Manual chart review was performed. Level of incontinence was assessed using Expanded Prostate Cancer Index Composite (EPIC) and pads per day (PPD) use. Satisfaction was assessed by willingness to recommend the procedure to a friend. Outcomes in men who received radiation were compared to radiation-naïve men.

RESULTS

Fifty-two men underwent AdVance sling placement. Eighteen men received adjuvant radiation. Thirty-six men were available for short term (19.4 months) and 16 men for long term (61.5 months) follow up. Overall, significant improvement was seen in post-sling EPIC score (24.6, p < 0.001), EPIC incontinence score (39.1, p < .001), and pad use (3.2 PPD to 1.4 PPD, p < .001). Greater improvement in EPIC scores and PPD use was seen in radiation-free men. Irradiated men were less satisfied with the procedure at both short and long term follow up. Diminished efficacy and satisfaction occurred at extended follow up for both groups but was more pronounced with radiation.

CONCLUSIONS

The majority of patients undergoing the AdVance sling procedure for post-prostatectomy urinary incontinence saw a significant reduction in pad use, and were overall satisfied in both radiated and non-radiated groups at short and long term follow up. However, improvements were greater in the non-radiated groups and diminished with time.

摘要

引言

我们回顾了使用AdVance吊带治疗前列腺切除术后尿失禁患者的经验,比较了辅助放疗在短期和长期随访中对吊带治疗成功率和患者满意度的影响。

材料与方法

使用当前操作术语(CPT)编码确定2007年至今接受AdVance吊带植入治疗前列腺切除术后尿失禁的男性患者。进行人工病历审查。使用扩展前列腺癌指数综合评分(EPIC)和每日使用尿垫数(PPD)评估尿失禁程度。通过是否愿意向朋友推荐该手术来评估满意度。将接受放疗的男性患者的结果与未接受放疗的男性患者进行比较。

结果

52名男性接受了AdVance吊带植入。18名男性接受了辅助放疗。36名男性可进行短期(19.4个月)随访,16名男性可进行长期(61.5个月)随访。总体而言,吊带术后EPIC评分(24.6,p < 0.001)、EPIC尿失禁评分(39.1,p < 0.001)和尿垫使用量(从3.2 PPD降至1.4 PPD,p < 0.001)均有显著改善。未接受放疗的男性患者在EPIC评分和PPD使用量方面改善更大。在短期和长期随访中,接受放疗的男性患者对该手术的满意度较低。两组在延长随访时疗效和满意度均有所下降,但放疗组更为明显。

结论

大多数接受AdVance吊带手术治疗前列腺切除术后尿失禁的患者尿垫使用量显著减少,在短期和长期随访中,放疗组和未放疗组总体上均感到满意。然而,未放疗组的改善更大,且随时间推移有所减少。

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