Toro-Ramos T, Kim Y, Wood M, Rajda J, Niejadlik K, Honcz J, Marrero D, Fawer A, Michaelides A
Noom, Inc, Clinical Research Department, New York, NY, USA.
Aetna, Inc, Hartford, CT, USA.
J Hum Hypertens. 2017 Dec;31(12):795-800. doi: 10.1038/jhh.2017.69. Epub 2017 Oct 3.
This pilot study evaluated the efficacy of a Hypertension Prevention Program (HPP) administered through a mobile application platform with human coaching (app) on reduction in blood pressure and weight in 50 adults with prehypertension or hypertension. Participants were recruited into a 24-week mobile application intervention to administer the HPP between January 2016 and July 2016. Dietary elements of the programme were based on the Dietary Approaches to Stop Hypertension. The programme included in-app human coaching with bi-weekly phone calls, meal logging, blood pressure tracking and educational material. Main outcome variables included change in systolic and diastolic blood pressure, hypertension category, and weight loss. Data were analysed between October 2016 and December 2016. The HPP yielded overall improvements in weight (-3.04±4.04 kg, P=<0.001), diastolic blood pressure (-5.06±11.89 mm Hg, P=0.004), and hypertension category (-0.48±0.74 mm Hg, P=<0.001). Sustained engagement of 80% resulted in significant reductions in systolic blood pressure (-7.75±12.56, P=<0.001) and weight (-3.73±4.01 kg, P<0.001) for programme completers, contributing to hypertension category change (-0.58±0.64 mm Hg, P<0.001). Mobile delivery of a lifestyle intervention for hypertension prevention showed short-term potential to reduce risk of hypertension, supporting the need for longer studies to investigate the use of mHealth lifestyle modification to reduce the risk of hypertension, a public health priority.
这项试点研究评估了通过移动应用程序平台并配备人工指导(应用程序)实施的高血压预防计划(HPP)对50名患有高血压前期或高血压的成年人降低血压和体重的效果。2016年1月至2016年7月期间,参与者被纳入一项为期24周的移动应用程序干预,以实施HPP。该计划的饮食元素基于“终止高血压膳食方法”。该计划包括应用程序内的人工指导、每两周一次的电话沟通、饮食记录、血压跟踪和教育材料。主要结局变量包括收缩压和舒张压的变化、高血压类别以及体重减轻。2016年10月至2016年12月期间对数据进行了分析。HPP在体重(-3.04±4.04千克,P<0.001)、舒张压(-5.06±11.89毫米汞柱,P=0.004)和高血压类别(-0.48±0.74毫米汞柱,P<0.001)方面总体上有所改善。80%的持续参与导致计划完成者的收缩压(-7.75±12.56,P<0.001)和体重(-3.73±4.01千克,P<0.001)显著降低,这有助于高血压类别发生变化(-0.58±0.64毫米汞柱,P<0.001)。通过移动方式提供预防高血压的生活方式干预显示出降低高血压风险的短期潜力,这支持了开展更长时间研究以调查使用移动健康生活方式改变来降低高血压风险的必要性,而高血压是一个公共卫生重点问题。