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酷似膀胱癌的原发性局限性膀胱淀粉样变性:一例报告

Primary Localized Vesical Amyloidosis Mimicking Bladder Carcinoma: A Case Report.

作者信息

Patil Purwa R, Warpe Bhushan M

机构信息

Department of Pathology, Grant Government Medical College and Sir J.J. Group of Hospitals, Byculla, Mumbai - 400008, India.

出版信息

Iran J Pathol. 2016 Fall;11(5):448-451. Epub 2016 Dec 24.

Abstract

Amyloidosis of urinary bladder is a rare condition and may be primary or secondary in nature. A case of primary localized vesical amyloidosis (VA) in a 40-yr-old man is described which was confused with neoplasm by cystoscopic, urographic and other studies. Surgical specimens obtained by transurethral resection (TUR) were diagnostic and histologically revealed amyloid deposits in sub-epithelial stroma with chronic inflammatory and giant-cell reaction. Congo-red staining proved its amyloid nature. It was resistant to potassium permanganate (KMnO) pretreatment, indicating it to be of the AL type.

摘要

膀胱淀粉样变是一种罕见疾病,本质上可能是原发性或继发性的。本文描述了一例40岁男性原发性局限性膀胱淀粉样变(VA)病例,该病例在膀胱镜检查、尿路造影及其他检查中被误诊为肿瘤。经尿道切除术(TUR)获取的手术标本具有诊断意义,组织学检查显示上皮下基质中有淀粉样沉积物,并伴有慢性炎症和巨细胞反应。刚果红染色证实了其淀粉样性质。它对高锰酸钾(KMnO)预处理有抗性,表明其为AL型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0959/5604108/be182a5b4b2c/ijp-11-448-g001.jpg

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