DeSouza Maria Alina, Rekhi Bharat, Thyavihally Yuvaraja B, Tongaonkar Hemant B, Desai Sangeeta B
Department of Pathology, Tata Memorial Hospital, Parel, Mumbai, India.
Indian J Pathol Microbiol. 2008 Jul-Sep;51(3):415-7. doi: 10.4103/0377-4929.42547.
Amyloidosis is characterized by extracellular deposition of a proteinaceous, hyaline material. Localized deposition of amyloid in individual organs is uncommon. It can occur in the absence of systemic involvement. Herein, we describe two cases of localized amyloidosis of the urinary bladder, which clinically, radiologically, and on cystoscopy masqueraded as bladder cancer. A diagnosis of amyloidosis in both these cases was ascertained on biopsy, supplemented with special stains.
淀粉样变性的特征是一种蛋白质样透明物质在细胞外沉积。淀粉样蛋白在单个器官中的局部沉积并不常见。它可在无全身受累的情况下发生。在此，我们描述两例膀胱局限性淀粉样变性病例，这两例在临床、放射学及膀胱镜检查时均表现为膀胱癌。通过活检并辅以特殊染色确定了这两例病例均为淀粉样变性。
