Gupta Prashant, Hanamshetti Satish, Kulkarni Jagdeesh N
Department of Urology, Bombay Hospital Institute of Medical Sciences, Mumbai, India.
J Cancer Res Ther. 2012 Apr-Jun;8(2):297-9. doi: 10.4103/0973-1482.98994.
Primary amyloidosis of bladder is a rare disease that closely resembles bladder cancer on clinical presentation with painless gross hematuria. Pathologically this is a totally benign non-neoplastic lesion and its association with urothelial carcinoma of the bladder is rare. We herein report a 64-year-old diabetic male who has been treated for primary amyloidosis of bladder for the last 26 years presented recently with high-grade solid urothelial cancer with osseous metaplasia and sarcomatoid change of bladder with area of amyloid deposition.
膀胱原发性淀粉样变性是一种罕见疾病，临床表现与膀胱癌极为相似，表现为无痛肉眼血尿。病理上，这是一种完全良性的非肿瘤性病变，与膀胱尿路上皮癌的关联罕见。我们在此报告一名64岁的糖尿病男性，他在过去26年里一直接受膀胱原发性淀粉样变性的治疗，最近出现了高级别实性尿路上皮癌，伴有骨化生以及膀胱肉瘤样改变，且存在淀粉样沉积区域。
