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乳腺原发性间质肉瘤:一种罕见的实体瘤。

Primary Stromal Sarcoma of Breast: A Rare Entity.

作者信息

Kumar Sanjay, Sharma Jyoti, Ralli Megha, Singh Gurpreet, Kalyan Sonu, Sen Rajeev

机构信息

Dept. of Pathology, PGIMS, Rohtak (Haryana), India.

出版信息

Iran J Pathol. 2016 Fall;11(5):469-473. Epub 2017 Jan 2.

PMID:28974969
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5604113/
Abstract

Primary soft tissue sarcomas of the breast constitute less than 5% of all soft tissue sarcomas and less than 1% of malignant breast cancers. The rarity of this tumor limits most studies to small retrospective case reviews and case reports. Primary breast sarcomas are locally aggressive tumors as evidenced by the high rate of local recurrence when excisional surgery is performed. A contemporary multidisciplinary approach to therapy including surgery, radiation, and chemotherapy is advocated. Herein, we report a case of 45-yr-old female, who presented with a large ulcerated breast mass and was diagnosed as carcinoma breast on fine needle aspiration. Modified radical masectomy was performed and was diagonsed with primary breast stromal sarcoma on histopathology, which is a rare entity.

摘要

乳腺原发性软组织肉瘤占所有软组织肉瘤的比例不到5%,占乳腺恶性肿瘤的比例不到1%。这种肿瘤的罕见性使得大多数研究局限于小型回顾性病例分析和病例报告。原发性乳腺肉瘤是局部侵袭性肿瘤,切除手术后局部复发率高就证明了这一点。提倡采用包括手术、放疗和化疗在内的现代多学科治疗方法。在此,我们报告一例45岁女性病例,该患者出现一个巨大的溃疡性乳腺肿块,细针穿刺活检诊断为乳腺癌。行改良根治性乳房切除术,组织病理学诊断为原发性乳腺间质肉瘤,这是一种罕见的疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c77a/5604113/997a5fa515fb/ijp-11-469-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c77a/5604113/f95d0d09e808/ijp-11-469-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c77a/5604113/234c61273ff4/ijp-11-469-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c77a/5604113/997a5fa515fb/ijp-11-469-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c77a/5604113/f95d0d09e808/ijp-11-469-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c77a/5604113/234c61273ff4/ijp-11-469-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c77a/5604113/997a5fa515fb/ijp-11-469-g003.jpg

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本文引用的文献

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Primary spindle cell sarcoma of the breast masquerading as necrotizing fasciitis.伪装成坏死性筋膜炎的乳腺原发性梭形细胞肉瘤。
J Surg Case Rep. 2014 Jan 27;2014(1):rjt096. doi: 10.1093/jscr/rjt096.
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Imaging features of primary breast sarcoma.原发性乳腺肉瘤的影像学特征。
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Mammary NOS-type sarcoma with CD10 expression: a rare entity with features of myoepithelial differentiation.伴有CD10表达的乳腺NOS型肉瘤:一种具有肌上皮分化特征的罕见实体。
乳腺原始未分化肉瘤大镜状脑转移:病例报告及文献复习。
CNS Oncol. 2022 Jun 1;11(2):CNS85. doi: 10.2217/cns-2022-0001. Epub 2022 May 10.
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Primary Breast Tumors with Mesenchymal Morphology.具有间叶形态的原发性乳腺肿瘤
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A rare case report of breast sarcoma.一例罕见的乳腺肉瘤病例报告。
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Cluster of Differentiation 10 Positive Stromal Sarcoma of Breast: A Diagnostic Challenge.乳腺分化簇10阳性间质肉瘤:一项诊断挑战。
Cureus. 2019 Jul 15;11(7):e5143. doi: 10.7759/cureus.5143.
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Primary breast sarcoma: clinicopathologic series from the Mayo Clinic and review of the literature.原发性乳腺肉瘤:梅奥诊所的临床病理系列研究及文献综述
Br J Cancer. 2004 Jul 19;91(2):237-41. doi: 10.1038/sj.bjc.6601920.
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Prognostic factors in primary breast sarcomas: a series of patients with long-term follow-up.原发性乳腺肉瘤的预后因素:一组长期随访的患者
J Clin Oncol. 2003 Jul 1;21(13):2583-8. doi: 10.1200/JCO.2003.06.080.
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Primary soft tissue sarcoma of the breast.乳腺原发性软组织肉瘤
Curr Treat Options Oncol. 2001 Apr;2(2):169-76. doi: 10.1007/s11864-001-0059-8.
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Sarcoma of the breast. A study of 32 patients with reappraisal of classification and therapy.乳腺肉瘤。对32例患者的研究及分类与治疗的重新评估。
Ann Surg. 1985 Apr;201(4):527-32. doi: 10.1097/00000658-198504000-00020.