Kumar Sanjay, Sharma Jyoti, Ralli Megha, Singh Gurpreet, Kalyan Sonu, Sen Rajeev
Dept. of Pathology, PGIMS, Rohtak (Haryana), India.
Iran J Pathol. 2016 Fall;11(5):469-473. Epub 2017 Jan 2.
Primary soft tissue sarcomas of the breast constitute less than 5% of all soft tissue sarcomas and less than 1% of malignant breast cancers. The rarity of this tumor limits most studies to small retrospective case reviews and case reports. Primary breast sarcomas are locally aggressive tumors as evidenced by the high rate of local recurrence when excisional surgery is performed. A contemporary multidisciplinary approach to therapy including surgery, radiation, and chemotherapy is advocated. Herein, we report a case of 45-yr-old female, who presented with a large ulcerated breast mass and was diagnosed as carcinoma breast on fine needle aspiration. Modified radical masectomy was performed and was diagonsed with primary breast stromal sarcoma on histopathology, which is a rare entity.
乳腺原发性软组织肉瘤占所有软组织肉瘤的比例不到5%,占乳腺恶性肿瘤的比例不到1%。这种肿瘤的罕见性使得大多数研究局限于小型回顾性病例分析和病例报告。原发性乳腺肉瘤是局部侵袭性肿瘤,切除手术后局部复发率高就证明了这一点。提倡采用包括手术、放疗和化疗在内的现代多学科治疗方法。在此,我们报告一例45岁女性病例,该患者出现一个巨大的溃疡性乳腺肿块,细针穿刺活检诊断为乳腺癌。行改良根治性乳房切除术,组织病理学诊断为原发性乳腺间质肉瘤,这是一种罕见的疾病。