Department of Neurosurgery, Centro Hospitalar Universitário Lisboa Norte EPE, Av. Professor Egas Moniz, 1649-035, Lisboa, Portugal.
CNS Oncol. 2022 Jun 1;11(2):CNS85. doi: 10.2217/cns-2022-0001. Epub 2022 May 10.
Primary breast sarcomas are rare high-grade tumors with a reported incidence of <1% of breast malignancies. Its dissemination to the CNS is exceptional and only one is found in the literature. The authors described the case of a 22-year-old female with history of a breast undifferentiated sarcoma that present with two large bilateral retrolenticular brain metastases. Both lesions were excised in the same procedure and she underwent adjuvant therapy. She died 24 months after surgery. Despite being aggressive lesions, aggressive treatment of primary breast sarcomas including brain metastases excision, should be considered in order to improve overall survival.
原发性乳腺肉瘤是一种罕见的高级别肿瘤，其发病率<1%的乳腺恶性肿瘤。其向中枢神经系统（CNS）播散是罕见的，在文献中仅发现一例。作者描述了一例 22 岁女性，患有乳腺未分化肉瘤，表现为双侧大的后晶状体脑转移。两个病变均在同一手术中切除，并接受了辅助治疗。她在手术后 24 个月死亡。尽管这些病变具有侵袭性，但对于包括脑转移切除在内的原发性乳腺肉瘤的积极治疗，应考虑以提高总体生存率。
