Nagaraj Praveen Birur, Ongole Ravikiran, Bhujanga-Rao Balaji Rao
Dept. of Oral Medicine & Radiology, KLE Society's Institute of Dental Sciences, India.
Med Oral Patol Oral Cir Bucal. 2006 Mar 1;11(2):E162-4.
Granular cell tumor is a relatively uncommon benign hamartomatous lesion occurring in almost any part of the body. The tongue and the buccal mucosa are common intra oral sites. Granular cell lesions may be found in other diverse sites such as the jaw, skin, gastro intestinal tract and respiratory tract. The histogenesis of the lesion still remains unknown. However, histochemical and ultra structural studies propose the origin of the lesion from schwann cells, striated muscle, mesenchymal cells, histiocytes and epithelial cells. The tumor generally occurs in middle or older aged adults. The lesion is typically seen as an uninflammed asymptomatic mass measuring about two cms in diameter with a yellowish surface coloration. As most of the granular cell tumors are benign, surgical excision of the lesion is the treatment of choice. We describe a case of granular cell tumor of the tongue in a 6 year old girl along with a brief review of literature on granular cell tumors.
颗粒细胞瘤是一种相对罕见的良性错构瘤性病变,几乎可发生于身体的任何部位。舌部和颊黏膜是口腔内常见的发病部位。颗粒细胞病变也可见于其他不同部位,如颌骨、皮肤、胃肠道和呼吸道。该病变的组织发生仍不清楚。然而,组织化学和超微结构研究提示该病变起源于施万细胞、横纹肌、间充质细胞、组织细胞和上皮细胞。该肿瘤通常发生于中老年人。病变通常表现为一个无炎症、无症状的肿块,直径约2厘米,表面呈淡黄色。由于大多数颗粒细胞瘤是良性的,手术切除病变是首选的治疗方法。我们报告一例6岁女孩舌部颗粒细胞瘤病例,并对颗粒细胞瘤的相关文献作一简要综述。