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孟加拉国弥漫性冠状动脉疾病患者行冠状动脉内膜切除术联合冠状动脉搭桥术的结局:一项回顾性队列研究。

Outcome of coronary endarterectomy with coronary artery bypass grafting in patients with diffuse coronary artery disease in Bangladesh: A retrospective cohort study.

作者信息

Ranjan Redoy, Adhikary Dipannita, Mandal Sabita, Seedher Anjali, Adhikary Asit Baran

机构信息

Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh.

Al Helal Specialized Hospital, Dhaka, Bangladesh.

出版信息

JRSM Cardiovasc Dis. 2017 Sep 20;6:2048004017732658. doi: 10.1177/2048004017732658. eCollection 2017 Jan-Dec.

Abstract

BACKGROUND

In this study, we aimed to review the consequences of coronary endarterectomy with coronary artery bypass grafting, and assess outcomes of this combined surgical technique for patients with diffuse coronary artery disease in a single surgeon's practice.

METHODS

We retrospectively reviewed outcome of 1198 endarterectomized coronary artery in 1000 patients with diffuse coronary artery disease, who have had experienced coronary endarterectomy with off pump coronary artery bypass grafting in between 2009 and 2016.

RESULTS

The mean age was 61.5 ± 5.5 years. Coronary endarterectomy was performed on 74.7% in the left coronary territory (43.2% left anterior descending, 26.6% diagonal, 4.9% Obtuse Marginal), and 25.3% in the right coronary territory. Post-operative intensive care unit mortality rate was 1.9%, and there were 11 (1.1%) late deaths. Mean intensive care unit stay was 36.6 ± 6.7 hours. Patients were extubated following a mean of 9.8 ± 1.25 hours. The mean duration of hospital stay was 10 ± 1 days. One-year survival rate was 97.8% and 89.5% survival rate was at 5 years follow up. However, 91.8% of patients were angina free at median follow-up of 2.5 years.

CONCLUSION

Coronary endarterectomy with off pump coronary artery bypass grafting is attainable and accomplishes surgical revascularization in coronary artery disease patients when there is no other alternative for sufficient revascularization.

摘要

背景

在本研究中,我们旨在回顾冠状动脉内膜切除术联合冠状动脉旁路移植术的后果,并评估在单一外科医生的实践中,这种联合手术技术对弥漫性冠状动脉疾病患者的治疗效果。

方法

我们回顾性分析了1000例弥漫性冠状动脉疾病患者中1198条接受内膜切除术的冠状动脉的治疗结果,这些患者在2009年至2016年间接受了非体外循环冠状动脉旁路移植术联合冠状动脉内膜切除术。

结果

患者平均年龄为61.5±5.5岁。74.7%的冠状动脉内膜切除术在左冠状动脉区域进行(43.2%为左前降支,26.6%为对角支,4.9%为钝缘支),25.3%在右冠状动脉区域进行。术后重症监护病房死亡率为1.9%,有11例(1.1%)晚期死亡。平均重症监护病房停留时间为36.6±6.7小时。患者平均在9.8±1.25小时后拔管。平均住院时间为10±1天。1年生存率为97.8%,5年随访生存率为89.5%。然而,在中位随访2.5年时,91.8%的患者无心绞痛。

结论

当没有其他足够的血运重建替代方案时,非体外循环冠状动脉旁路移植术联合冠状动脉内膜切除术对于冠状动脉疾病患者是可行的,并且能够实现手术血运重建。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d079/5613798/8e8d26762c9e/10.1177_2048004017732658-fig1.jpg

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