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非体外循环冠状动脉搭桥术联合冠状动脉内膜切除术

Coronary endarterectomy with off-pump coronary artery bypass surgery.

作者信息

Eryilmaz Sadik, Inan Mustafa Bahadir, Eren Neyyir Tuncay, Yazicioglu Levent, Corapcioğlu Tumer, Akalin Hakki

机构信息

Department of Cardiovascular Surgery, Ankara University School of Medicine, Ankara, Turkey.

出版信息

Ann Thorac Surg. 2003 Mar;75(3):865-9. doi: 10.1016/s0003-4975(02)04500-9.

Abstract

BACKGROUND

The aim of this study is to review our experience in coronary artery endarterectomy performed without cardiopulmonary bypass.

METHODS

Between May 1998 and June 2000 off-pump coronary endarterectomy was performed on 11 patients who had unstable angina pectoris. The mean ejection fraction (EF) was 26.3 +/- 4.4, and all of the patients were New York Heart Association (NYHA) III or IV. Off-pump open left anterior descending (LAD) endarterectomy was performed on 7 patients, and closed endarterectomy of the right coronary artery (RCA) was done on the remaining 4.

RESULTS

There were no deaths. None of the procedures was converted to on-pump operation; all the endarterectomies and bypasses were performed on the beating heart. All patients were completely revascularized, the left internal mammary artery was bypassed to the LAD in all operations, and all other grafts were of saphenous vein. At the end of the first year all bypasses to the endarterectomized arteries were patent. The overall patency rate was 95.6%. The mean postoperative EF was 34.7 +/- 9.1, which was significantly higher than the preoperative one (p < 0.05). At the end of the first year 9 patients were NYHA I or II and all were angina free in Canadian Cardiovascular Society class 0 or I.

CONCLUSIONS

Endarterectomy without cardiopulmonary bypass can be performed in patients with severe left ventricular dysfunction who are expected to benefit from the complete revascularization.

摘要

背景

本研究的目的是回顾我们在非体外循环下进行冠状动脉内膜切除术的经验。

方法

1998年5月至2000年6月期间,对11例不稳定型心绞痛患者进行了非体外循环冠状动脉内膜切除术。平均射血分数(EF)为26.3±4.4,所有患者均为纽约心脏协会(NYHA)III级或IV级。7例患者进行了非体外循环下开放左前降支(LAD)内膜切除术,其余4例进行了右冠状动脉(RCA)闭合内膜切除术。

结果

无死亡病例。所有手术均未转为体外循环手术;所有内膜切除术和旁路手术均在心脏跳动时进行。所有患者均实现完全血运重建,所有手术中左乳内动脉均旁路移植至LAD,所有其他移植物均为大隐静脉。在第一年年底,所有内膜切除动脉的旁路移植血管均通畅。总体通畅率为95.6%。术后平均EF为34.7±9.1,显著高于术前(p<0.05)。在第一年年底,9例患者为NYHA I级或II级,所有患者加拿大心血管学会心绞痛分级均为0级或I级,无心绞痛症状。

结论

对于预期能从完全血运重建中获益的严重左心室功能不全患者,可以进行非体外循环下的内膜切除术。

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