双侧苍白球深部脑刺激治疗难治性眼睑痉挛
Intractable Blepharospasm Treated with Bilateral Pallidal Deep Brain Stimulation.
作者信息
Luthra Nijee S, Mitchell Kyle T, Volz Monica M, Tamir Idit, Starr Phillip A, Ostrem Jill L
机构信息
Department of Neurology, University of California, San Francisco, CA, USA.
Department of Neurosurgery, University of California, San Francisco, CA, USA.
出版信息
Tremor Other Hyperkinet Mov (N Y). 2017 Jul 6;7:472. doi: 10.7916/D8SJ1V9F. eCollection 2017.
BACKGROUND
Blepharospasm can be present as an isolated dystonia or in conjunction with other forms of cranial dystonia, causing significant disability.
CASE REPORT
We report a case of a 69-year-old male with craniocervical dystonia, manifesting primarily as incapacitating blepharospasm refractory to medical treatments. He underwent bilateral globus pallidus (GP) deep brain stimulation (DBS) with complete resolution of his blepharospasm and sustained benefit at 12 months postoperatively.
DISCUSSION
This case illustrates successful treatment of blepharospasm with pallidal stimulation. GP-DBS should be considered a reasonable therapeutic option for intractable blepharospasm.
背景
眼睑痉挛可表现为孤立性肌张力障碍，或与其他形式的颅肌张力障碍合并出现，导致严重残疾。
病例报告
我们报告一例69岁男性患有颅颈肌张力障碍，主要表现为药物治疗无效的致残性眼睑痉挛。他接受了双侧苍白球（GP）深部脑刺激（DBS）治疗，眼睑痉挛完全缓解，术后12个月持续受益。
讨论
该病例说明了苍白球刺激对眼睑痉挛的成功治疗。对于难治性眼睑痉挛，GP-DBS应被视为一种合理的治疗选择。
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