Murthy Vedang, Calcuttawala Adnan, Chadha Kirti, d'Cruz Anil, Krishnamurthy Arvind, Mallick Indranil, Nair Sudhir, Teni Tanuja, Pawar Sagar, Talapatra Kaustav, Patil Asawari, Bhatt Amit, Chatterjee Sanjoy, Swain Monali, Narayanan Prasad, Ghadyalpatil Nikhil, Singhal Manish, Kuriakose Moni, Prabhash Kumar, Agarwal Jaiprakash, Parikh Purvish
Department of Radiation Oncology, Tata Memorial Centre, Mumbai, Maharashtra, India.
Department of Oncopathology, Metropolis Healthcare Ltd., Mumbai, Maharashtra, India.
South Asian J Cancer. 2017 Jul-Sep;6(3):93-98. doi: 10.4103/sajc.sajc_96_17.
Human papillomavirus (HPV) associated head and neck squamous cell cancers (HNSCC) have become increasingly common in the West, but the same cannot be said about India. These cancers have a different biology and confer a better prognosis, however, its current role in the management of patients in India is not clearly defined. At the 35 Indian Cooperative Oncology Network conference held in September 2016, a panel of radiation, surgical and medical oncologists, pathologists, and basic scientists from across the country having experience in clinical research with respect to HPV in HNSCC reviewed the available literature from India. All the ideas and facts were thereafter collated in this report. Various topics of controversy in dealing with the diagnosis and management of HPV-associated HNSCC have been highlighted in this report in context to the Indian scenario. Furthermore, the prevalence of the same and its association with tobacco and high-risk sexual behavior has been touched on. Conclusively, a set of recommendations has been proposed by the panel to guide the practicing oncologists of the country while dealing with HPV-associated HNSCC.
人乳头瘤病毒（HPV）相关的头颈部鳞状细胞癌（HNSCC）在西方日益常见，但在印度情况并非如此。这些癌症具有不同的生物学特性，预后较好，然而，其目前在印度患者管理中的作用尚未明确界定。在2016年9月举行的第35届印度肿瘤协作网络会议上，来自全国各地的一组放疗、外科和医学肿瘤学家、病理学家以及基础科学家，他们在HPV相关HNSCC的临床研究方面具有经验，对来自印度的现有文献进行了回顾。此后，所有的观点和事实都整理在本报告中。本报告结合印度的情况，突出了在处理HPV相关HNSCC的诊断和管理方面存在争议的各种主题。此外，还涉及了其患病率及其与烟草和高危性行为的关联。最后，该小组提出了一系列建议，以指导该国执业肿瘤学家处理HPV相关HNSCC。
