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体重指数在30至35之间的患者行袖状胃切除术后的结果——3年随访

Sleeve Gastrectomy Outcomes in Patients with BMI Between 30 and 35-3 Years of Follow-Up.

作者信息

Berry Marcos A, Urrutia Lionel, Lamoza Patricio, Molina Alfredo, Luna Eduardo, Parra Federico, Domínguez María J, Alonso Rodrigo

机构信息

Bariatric and Metabolic Center, Department of Surgery, Clinica Las Condes, Lo Fontecilla 441, Las Condes, Santiago, Chile.

出版信息

Obes Surg. 2018 Mar;28(3):649-655. doi: 10.1007/s11695-017-2897-x.

Abstract

INTRODUCTION AND PURPOSE

Laparoscopic sleeve gastrectomy (LSG) in patients with a BMI between 30 and 35 kg/m plus comorbidities has shown to be safe and effective. The purpose of this study is to describe our outcomes in this group of patients after 3 years of follow-up.

MATERIALS AND METHODS

Retrospective descriptive analysis of patients with initial BMI between 30 and 35 kg/m plus comorbidities were submitted to LSG between 2006 and 2013. We analyzed gender, age, comorbidities, BMI, total weight loss (%TWL), excess weight loss (%EWL), comorbidity resolution, morbidity, and mortality. Postoperative success was defined as %TWL over 20% and EWL% over 50% maintained for at least 1 year and comorbidity remission with no need of medication.

RESULTS

Of the patients, 477 underwent a LSG in the above period and 252 met inclusion criteria; 188 (75%) were female and 64 (25%) were male. Median age was 39 years (15-70). Three-year follow-up was 43.9% (111 patients). Median preoperative BMI was 32.3 kg/m (30-34.3). Median postoperative %TWL was 12.9, 23.2, 28.2, 24.3, and 22.1% at 1, 6, 12, 24, and 36 months, respectively. %EWL was 42.88, 77.44, 98.42, 83.2, and 75.8%. Median surgical time was 86.9 min (40-120). There was comorbidity remission at 36 months. Insulin resistance was remitted in 89.4%, dyslipidemia 52%, non-alcoholic fatty liver disease 84.6%, hypertension 75%, and GERD 65%. T2DM had 60% of complete remission and 40% improvement. There were morbidity in six patients (2.4%), two reoperations, no leaks, and no mortality.

CONCLUSIONS

Performing LSG in patients with grade I obesity is safe and effective. BMI should not be the only indicator to consider bariatric and metabolic surgery. We still require further studies and longer follow-up.

摘要

引言与目的

对于体重指数(BMI)在30至35kg/m²且伴有合并症的患者,腹腔镜袖状胃切除术(LSG)已被证明是安全有效的。本研究的目的是描述该组患者在3年随访后的结果。

材料与方法

对2006年至2013年间接受LSG手术、初始BMI在30至35kg/m²且伴有合并症的患者进行回顾性描述性分析。我们分析了性别、年龄、合并症、BMI、总体重减轻百分比(%TWL)、超重减轻百分比(%EWL)、合并症缓解情况、发病率和死亡率。术后成功定义为%TWL超过20%且EWL%超过50%,并持续至少1年,同时合并症缓解且无需药物治疗。

结果

在此期间,477例患者接受了LSG手术,252例符合纳入标准;其中188例(75%)为女性,64例(25%)为男性。中位年龄为39岁(15 - 70岁)。三年随访率为43.9%(111例患者)。术前中位BMI为32.3kg/m²(30 - 34.3)。术后1、6、12、24和36个月时,中位%TWL分别为12.9%、23.2%、28.2%、24.3%和22.1%。%EWL分别为42.88%、77.44%、98.42%、83.2%和75.8%。中位手术时间为86.9分钟(40 - 120分钟)。36个月时合并症得到缓解。胰岛素抵抗缓解率为89.4%,血脂异常为52%,非酒精性脂肪性肝病为84.6%,高血压为75%,胃食管反流病为65%。2型糖尿病完全缓解率为60%,改善率为40%。6例患者(2.4%)出现并发症,2例再次手术,无吻合口漏,无死亡病例。

结论

对I级肥胖患者进行LSG手术是安全有效的。BMI不应是考虑进行减重代谢手术的唯一指标。我们仍需要进一步研究和更长时间的随访。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/574c/5803286/052d4ba70c77/11695_2017_2897_Fig1_HTML.jpg

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