Dobrev Hristo P, Atanasov Nikolay G, Dimitrova Donka D
Department of Dermatology and Venereology, Faculty of Medicine, Medical University of Plovdiv, Plovdiv, Bulgaria
Department of Health Management and Health Economics, Faculty of Public Health, Medical University of Plovdiv, Plovdiv, Bulgaria
Folia Med (Plovdiv). 2017 Sep 1;59(3):326-335. doi: 10.1515/folmed-2017-0041.
Psoriasis vulgaris (PsV) is a chronic skin condition that has a major impact on health-related quality of life (HRQOL).
To determine the individual burden of PsV on HRQOL using willingness to pay (WTP) instrument.
Fifty-one consecutive PsV patients were asked to evaluate their overall health and psoriasis affected health by visual analogue scale (VAS), and interviewed on 8 domains (physical, emotional, sleep, work, social, self-care, intimacy, and concentration) of HRQOL and WTP for a hypothetical cure in each domain. Two additional questions proposing 6 alternatives for therapy were also asked. The analysis is performed with descriptive and frequency statistics, Mann-Whitney and Kruskal-Wallis tests.
The domains ranked highly were: physical comfort (90%), social comfort (77%), emotional health (75%) and work (53%). The following tendencies concerning WTP for top four impacted domains were found: the median WTP were the highest in the top impacted domains; the younger patients were willing to pay more than the older ones; the highest median WTP amounts appear in the lowest income group; the highest median WTP is associated with smaller psoriasis affected health VAS scores. The largest proportion and number of patients (37.3%, n=19) stated preferences for the systemic therapy. The second preferred choice was the thalassotherapy (29.4%, n=15).
The utility and reliability of the instrument based on the assessment of WTP stated preferences for 8 domains of HRQOL for evaluation the individual burden of psoriasis were strongly supported.
寻常型银屑病(PsV)是一种慢性皮肤病,对健康相关生活质量(HRQOL)有重大影响。
使用支付意愿(WTP)工具确定PsV对HRQOL的个体负担。
连续51例PsV患者被要求通过视觉模拟量表(VAS)评估其整体健康状况和银屑病对健康的影响,并就HRQOL的8个领域(身体、情绪、睡眠、工作、社交、自我护理、亲密关系和注意力)以及每个领域假设治愈的WTP进行访谈。还询问了另外两个提出6种治疗方案的问题。采用描述性和频率统计、Mann-Whitney检验和Kruskal-Wallis检验进行分析。
排名靠前的领域是:身体舒适度(90%)、社交舒适度(77%)、情绪健康(75%)和工作(53%)。发现了关于前四个受影响领域WTP的以下趋势:受影响最大的领域中WTP中位数最高;年轻患者比老年患者愿意支付更多;WTP中位数最高出现在收入最低的群体中;WTP中位数最高与银屑病对健康影响的VAS评分较低相关。最大比例和数量的患者(37.3%,n = 19)表示倾向于全身治疗。第二受欢迎的选择是海水疗法(29.4%,n = 15)。
基于对WTP评估的工具用于评估银屑病个体负担,在HRQOL的8个领域陈述偏好方面的效用和可靠性得到了有力支持。