Bartzsch Stefan, Oelfke Uwe
The Institute Of Cancer Research, 123 Old Brompton Road, London SW7 3RP, United Kingdom. Department of Radiation Oncology, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Straße 22, 81675 Munich, Germany.
Phys Med Biol. 2017 Oct 27;62(22):8600-8615. doi: 10.1088/1361-6560/aa910b.
Currently hard coherent x-ray radiation at high photon fluxes can only be produced with large and expensive radiation sources, such as 3[Formula: see text] generation synchrotrons. Especially in medicine, this limitation prevents various promising developments in imaging and therapy from being translated into clinical practice. Here we present a new concept of highly brilliant x-ray sources, line focus x-ray tubes (LFXTs), which may serve as a powerful and cheap alternative to synchrotrons and a range of other existing technologies. LFXTs employ an extremely thin focal spot and a rapidly rotating target for the electron beam which causes a change in the physical mechanism of target heating, allowing higher electron beam intensities at the focal spot. Monte Carlo simulations and numeric solutions of the heat equation are used to predict the characteristics of the LFXT. In terms of photon flux and coherence length, the performance of the line focus x-ray tube compares with inverse Compton scattering sources. Dose rates of up to 180 Gy [Formula: see text] can be reached in 50 cm distance from the focal spot. The results demonstrate that the line focus tube can serve as a powerful compact source for phase contrast imaging and microbeam radiation therapy. The production of a prototype seems technically feasible.
目前,高光子通量的硬相干X射线辐射只能通过大型且昂贵的辐射源产生,例如第三代同步加速器。特别是在医学领域,这种限制阻碍了成像和治疗方面各种有前景的进展转化为临床实践。在此,我们提出一种高亮度X射线源的新概念——线聚焦X射线管(LFXTs),它可能成为同步加速器和一系列其他现有技术的强大且廉价的替代方案。LFXTs采用极细的焦点和用于电子束的快速旋转靶材,这会导致靶材加热的物理机制发生变化,从而允许在焦点处有更高的电子束强度。利用蒙特卡罗模拟和热方程的数值解来预测LFXT的特性。就光子通量和相干长度而言,线聚焦X射线管的性能可与逆康普顿散射源相媲美。在距焦点50厘米的距离处,剂量率可达180 Gy [公式:见正文]。结果表明,线聚焦管可作为用于相衬成像和微束放射治疗的强大紧凑型源。制造一个原型在技术上似乎是可行的。