Rotimi V O, Laughon B E, Bartlett J G, Mosadomi H A
Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.
Antimicrob Agents Chemother. 1988 Apr;32(4):598-600. doi: 10.1128/AAC.32.4.598.
The in vitro activities of extracts of Nigerian chewing sticks against Bacteroides gingivalis and B. melaninogenicus are presented. The greatest inhibitory action was produced by Serindeia werneckei, whereas Fagara zanthoxyloides produced no appreciable inhibitory effect. A generally good correlation was found between the killing curves and MICs. Only extracts of Anogeissus leiocarpus showed acute toxicity in mice.
本文展示了尼日利亚咀嚼棒提取物对牙龈拟杆菌和产黑色素拟杆菌的体外活性。韦氏绢毛猴木提取物产生的抑制作用最强,而花椒提取物未产生明显的抑制作用。在杀菌曲线和最低抑菌浓度之间发现了普遍良好的相关性。只有非洲臀果木提取物在小鼠中显示出急性毒性。