感染性心内膜炎与甘露糖结合凝集素缺乏——病例报告
Infective endocarditis and mannose-binding lectin deficiency - A case report.
作者信息
Watson Ximena, Parris Mike
机构信息
St George's Hospital, Tooting, London, UK.
Ashford and St Peter's Hospital Trust, Chertesy, Surrey, UK.
出版信息
J Intensive Care Soc. 2015 Nov;16(4):355-358. doi: 10.1177/1751143715581392. Epub 2015 Apr 22.
Abstract
We present the case of a 40-year-old woman diagnosed with Austrian syndrome, an association of endocarditis, meningitis and pneumonia caused by . She had none of the risk factors previously described in the literature but on immunological assay was found to have low serum levels of mannose-binding lectin, a protein required for complement activation. The clinical manifestation and treatment of this condition are discussed, and we emphasize the importance of early recognition of cardiac involvement and prompt surgical management.
摘要
我们报告了一例40岁女性被诊断为奥地利综合征的病例，该综合征是由……引起的心内膜炎、脑膜炎和肺炎的一种关联疾病。她没有文献中先前描述的任何危险因素，但在免疫测定中发现其血清中甘露糖结合凝集素水平较低，甘露糖结合凝集素是补体激活所需的一种蛋白质。本文讨论了该疾病的临床表现和治疗方法，并强调了早期识别心脏受累情况及及时进行手术治疗的重要性。
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引用本文的文献
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[Austrian syndrome: A rare manifestation of invasive pneumococcal disease. A case report and bibliographic review].[奥地利综合征：侵袭性肺炎球菌病的一种罕见表现。病例报告及文献综述]
Rev Esp Quimioter. 2019 Apr;32(2):98-113. Epub 2019 Mar 15.
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